Effect of Intradialytic Continuous Versus Interval Aerobic Exercises on Functional Capacity Quality of Life and in Patients With Chronic Renal Failure.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 67
- 试验地点
- 2
- 主要终点
- Kidney Disease Quality of Life Questionnaire -SF36(KDQoL-SF36)
研究概览
简要总结
Chronic kidney disease has emerged as one of the leading causes of mortality worldwide, and it is one of a small number of non-communicable diseases that have shown an increase in associated deaths over the past 2 decades. The high number of affected individuals and the significant adverse impact of chronic kidney disease should prompt enhanced efforts for better prevention and treatment.
Chronic kidney disease is a serious medical problem, as it is associated with high risks of complications which lead to poor quality of life and physical capacity.
详细描述
Sixty-seven patients undergoing haemodialysis randomly be allocated into three groups, (A, B & C). Group A (low- to moderate-continuous intensity cycling exercises, group B (moderate- to high-interval intensity cycling exercises), the exercises performed two sessions per week for two months and group (C)Twenty three patients received the hemodialysis sessions only.
Group A (low- to moderate-continuous intensity cycling exercises:
Twenty three patients performed aerobic exercise during dialysis using Pedal machine at low- to moderate continuous intensity rating from 11 to 13 on the Borg scale for 15-30 minutes.
warming up and cool down (approximately 10 minutes) in form of free active exercise of the lower extremities.
Group B (moderate- to high-interval intensity cycling exercises), Twenty one patients performed aerobic exercise during dialysis using Pedal machine at moderate-to-high interval intensity rating from 12 to 15 on the Borg scale for 15-30 minutes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
single (participant)
入排标准
- 年龄范围
- 35 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Sixty-seven patients of both sexes
- •Age will range from 35-55 years old.
- •BMI will be from 25-34.5 Kg/m
- •All patients with stage 5 of CRF.
- •All patients are stable on dialysis for at least six months before the study.
- •Stable medical and clinical hemodynamic state.
排除标准
- •Patients with hearing impairment or mental disorder.
- •Patients with unstable angina, uncontrolled cardiac arrhythmia, decompensated heart failure, persistent systolic blood pressure (BP) greater than 200 mmHg, persistent diastolic BP greater than 120 mmHg, acute pericarditis or myocarditis.
- •Patients with auto-immune diseases.
- •Chronic inflammatory orthopedic disorders and rheumatoid arthritis.
- •Patients with history of neuromuscular disease (muscular dystrophy, myasthenia gravis, myopathy, multiple sclerosis and peripheral neuropathy).
- •Patients with chronic obstructive lung disease, restrictive lung disease or chronic chest infection.
- •Patients with BMI > 35Kg/m2.
结局指标
主要结局
Kidney Disease Quality of Life Questionnaire -SF36(KDQoL-SF36)
时间窗: pre and post treatment after 2 months
The KDQOL™-36 contains 5 subscales: The Physical Component Summary (PCS), Mental Component Summary (MCS), Burden of Kidney Disease (BKD), Symptoms and Problems of Kidney Disease (SPKD), and Effects of Kidney Disease (EKD). The first 2 subscales are a generic measure of HRQOL (and are identical to the SF-12), whereas the last 3 assess issues specific to patients with ESRD or earlier stages of chronic kidney disease.
次要结局
- blood urea, serum creatinine(pre and post treatment after 2 months)
- 6-min walk distance(pre and post treatment after 2 months)
研究者
Heba Ahmed Mousa Galeb
Lecturer at the Department of Physical Therapy for Cardiovascular /Respiratory Disorders and Geriatrics Faculty of Physical Therapy
Cairo University