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Topical Ocular Mecamylamine in Diabetic Macular Edema (DME)

Phase 2
Completed
Conditions
Diabetic Macular Edema
Registration Number
NCT00536692
Lead Sponsor
CoMentis
Brief Summary

This is an open-label study evaluating the safety and tolerability of topical ocular mecamylamine given twice a day in patients with diabetic macular edema (DME). Patients will be treated for 12 weeks.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • macular edema due to diabetic retinopathy
Exclusion Criteria
  • vision loss from other ocular disease
  • intraocular surgery within 3 months
  • intraocular anti-VEGF or steroids within 3 months
  • HbA1c >12

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (3)

Ophthalmic Consultants of Boston

🇺🇸

Boston, Massachusetts, United States

Johns Hopkins School of Medicine / Wilmer Eye Institute

🇺🇸

Baltimore, Maryland, United States

East Bay Retina Consultants, Inc.

🇺🇸

Oakland, California, United States

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