CTRI/2025/07/090020尚未招募2/3 期
Efficacy of a eight week life style modification programme (yoga, diet and counselling) on Gut microbial diversity in Asthmatics
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Percentage of beneficial gut microbiota (probiotics) as measured by shotgun metagenome sequencing.
研究概览
简要总结
The goal of the study is to assess the diversity of gut microbiota and the metabolites produced by the bacteria in asthmatics. To measure the population of beneficial bacteria and the presence or absence of pathogenic microorganisms.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 35.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Both male and female aged between 35 and 70.
排除标准
- •a)Participants have other respiratory complications such as Emphysema, Tuberculosis, Pulmonary fibrosis, etc.
- •Hypertension, and Tuberculosis.
- •b)Participants consume drugs and steroids c)Participants have severe Neurological and Psychiatric disorders.
- •d)Participants with severe Insomnia and other co-morbidity.
结局指标
主要结局
Percentage of beneficial gut microbiota (probiotics) as measured by shotgun metagenome sequencing.
时间窗: These will be assessed at baseline (Week 0) and post-intervention (Week 8).
Presence or absence of pathogenic bacteria and fungi in the intestinal microbiome.
时间窗: These will be assessed at baseline (Week 0) and post-intervention (Week 8).
次要结局
- Antibiotic resistance against common antibiotics(Metabolites such as vitamins, Neurotransmitters, & SCFAS (Short chain fatty acids) before & after the interventions based on the algorithm-based output.)
研究者
Sanjib Patra
Central University of Rajasthan
研究点 (1)
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