Effects of Resistance-band Training and Creatine and Whey Protein

Not Applicable

Recruiting

• Conditions: Sarcopenia in Elderly
• Interventions: Dietary Supplement: Creatine Whey Protein; Dietary Supplement: Whey Protein

• Registration Number: NCT06606717
• Lead Sponsor: University of Regina

Brief Summary

The primary purpose of this research is to compare the effects of creatine monohydrate and/or whey protein supplementation during the first 10 weeks of a 20-week resistance-band training program on measures of body composition (whole-body lean tissue mass, total body water), arm and leg muscle thickness, upper- and lower-body muscle performance (i.e., strength, endurance) and functional ability (walking speed, balance). A secondary purpose of this research is to examine the effects of supplementation cessation (i.e., no creatine and/or whey protein supplementation) during the final 10 weeks of the 20-week resistance-band training program on these measures.

Detailed Description

Sarcopenia, characterized by the age-related reduction in strength, muscle mass, and physical function, decreases the ability to perform activities of daily living. Physical inactivity and inadequate nutrition are contributing factors to the development of sarcopenia. Resistance training is a safe, viable and effective intervention which increases measures of muscle and bone mass, muscle performance (i.e., strength, endurance) and functional ability in older adults. However, older adults indicate that high costs and difficulty finding training programming and/or facilities are barriers to participating in resistance training. Home-based resistance-band training is safe, effective and serves as a viable alternative to traditional resistance training (i.e., involving free-weights and machine-based equipment). From a healthy aging perspective, resistance-band training elicits similar improvements in strength (primary indicator of sarcopenia) and functional ability compared to traditional resistance training in older adults. In addition to resistance training (involving resistance-bands), creatine and whey protein supplementations have also been shown to have favorable effects on measures of muscle, bone and functional ability in older adults. However, no study has examined the effects of resistance-band training and creatine and whey protein supplementation in older adults.

Study Timeline

• Study Start: 2024-08-18
• Status Verified: 2024-09
• Study First Submitted: 2024-09-16
• Study First Submitted QC: 2024-09-18
• Last Update Submitted: 2024-09-18
• Study First Posted: 2024-09-23
• Last Update Posted: 2024-09-23
• Primary Completion: 2025-07
• Study Completion: 2025-07

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• Untrained (defined as those performing ≤ 1 resistance training session per week for ≥ 6 weeks prior to the start of the study)

Exclusion Criteria

• Taking creatine monohydrate within 30 days prior to the start of the study
• Currently ingesting whey protein
• Have pre-existing allergies to latex, fruit, dairy, nuts, seafood and mustard

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Creatine Whey Protein	Creatine Whey Protein	-
Whey Protein	Whey Protein	-

Primary Outcome Measures

Name	Time	Method
Whole-body lean mass (kg)	baseline, week 10, week 20	Bioelectrical impedance analysis
Strength (kg)	baseline, week 10, week 20	1-repetition maximum leg press and chest press
Endurance (number of repetitions to fatigue)	baseline, week 10, week 20	Leg press and chest press
Balance (Centre of Pressure)	baseline, week 10, week 20	Force Plate
Hydration (kg)	baseline, week 10, week 20	Bioelectrical impedance analysis
Gait Speed (meters)	baseline, week 10, week 20	Walking distance
Muscle Hypertrophy (cm)	baseline, week 10, week 20	B-mode ultrasound

Trial Locations

Locations (1)

University of Regina; 🇨🇦 Regina, Saskatchewan, Canada