Effects of Resistance-band Training and Creatine Supplementation in Healthy Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 52
- 试验地点
- 2
- 主要终点
- Whole-body lean mass (kg)
研究概览
简要总结
The primary purpose is to compare the effects of creatine supplementation (bolus ingestion of 5 grams vs. 3 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).
A secondary purpose of this research is to examine the effects of bolus ingestion of creatine (5 grams) compared to intermittent ingestion of creatine (2 x 2.5 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).
详细描述
Resistance-band training is safe, conveient, easy-to-use, eliminates potential barriers to exercise participation (i.e., lack of transportation to and from commercial training facilities) and results in high exercise compliance and adherence. Further, resistance-band training results in similar improvements in muscle performance and functional ability compared to traditional resistance-type training using free-weights and machines.
Creatine is a naturally occurring nitrogen-containing compound produced in the body in the liver and brain and can also be found in food products such as red meat and seafood or through commercially available manufactured creatine products.
Evidence-based research shows that creatine supplementation, when ingested during a resistance exercise training program, improves measures of lean mass and muscle growth, muscle performance and functional ability. However, the optimal creatine supplementation protocol to achieve these benefits is unknown.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •if you are 50 years of age and older
- •if you have not been performing more than 1 resistance training session per week for the past 6 weeks or more.
排除标准
- •if you have taken creatine supplements within 30 days prior to the start of the study
- •if you have pre-existing allergies to the placebo (corn-starch maltodextrin).
结局指标
主要结局
Whole-body lean mass (kg)
时间窗: baseline, week 16
Bioelectrical impedance analysis
Muscle Hypertrophy (cm)
时间窗: baseline, week 16
B-mode ultrasound
Strength (kg)
时间窗: baseline, week 16
1-repetition maximum leg press and chest press
Endurance (number of repetitions to fatigue)
时间窗: baseline, week 16
Leg press and chest press
Power (feet)
时间窗: baseline, week 16
medicine ball throw
Balance (Centre of Pressure)
时间窗: baseline, week 16
Force Plate
Gait Speed (meters)
时间窗: baseline, week 16
Walking distance
次要结局
未报告次要终点
研究者
Darren Candow
Professor
University of Regina