The Effect of Milk Derived Protein Supplementation on Muscle Recovery Following Resistance Exercise
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- Change in Muscle Contractile Function
研究概览
简要总结
The focus is performance nutrition. Resistance exercise can induce low level muscle damage in conjunction with impaired contractile function. Milk-derived proteins contain, or induce, bioactive properties that assist muscle recovery and restore/improve muscle function. The aim of the research is the recovery of muscle function following resistance exercise.
In this study, the investigators propose to undertake a comparison of the ingestion of two milk-derived protein-based recovery drinks on muscle function after resistance exercise compares to an isonitrogenous, non-essential amino acid control.
详细描述
Study Design: A block randomised design of 3 groups of resistance-exercise trained (RET) men
Participants: 24 young, healthy, resistance exercise trained, males aged 18 - 35 years.
Recovery drinks; CONTROL - an isonitrogenous, non-essential amino acid solution; PROTEIN - a milk-based whey protein concentrate (WPC), WPC-80; HYDROLYSATE - a hydrolysed derivative of WPC-80.
Day 1, Pre-screening consisting of:
- medical history and examination by a clinician
- blood sample to be evaluated for health-related contraindications
- body composition measurement by dual energy x-ray absorptiometry (DXA) to determine whole body and segmental lean tissue mass;
- exercise training log (6 month recall);
- dietary consultation;
- habitual physical activity level assessed by European Physical Activity Questionaire (EPAQ)-2
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
盲法说明
Double blind (participant and investigator)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •no known current illness or physically active
- •resistance-exercise trained
- •no known intolerance to milk-based products
- •no known blood born disease or medication that would adversely affect participation
- •no adverse risk to venepuncture
排除标准
- •recent musculoskeletal injury
研究组 & 干预措施
CONTROL
Intervention: Dietary Supplement: Non-essential amino acids A group of subjects ingesting a liquid beverage (per kilogram body mass: 0.33g non-essential amino acids dissolved in water ) prior to completion of a prescribed resistance exercise training (RET) session.
Muscle Contractile Function to be conducted prior to and following the RET session by laboratory-based ergometry.
Muscle Protein Synthesis induced by RET to be measured by deuterium incorporation in to skeletal muscle sampled by microbiopsy.
干预措施: CONTROL (Dietary Supplement)
HYDROLYSATE
Intervention: Dietary Supplement: Whey Protein Hydrolysate A group of subjects ingesting a liquid beverage (per kilogram body mass: 0.33g of Whey Protein Hydrolysate dissolved in water ) prior to completion of a prescribed resistance exercise training (RET) session.
Muscle Contractile Function to be conducted prior to and following the RET session by laboratory-based ergometry. Muscle Protein Synthesis induced by RET to be measured by deuterium incorporation in to skeletal muscle sampled by microbiopsy.
干预措施: Whey Protein Hydrolysate (Dietary Supplement)
PROTEIN
Intervention: Dietary Supplement: Whey Protein Concentrate A group of subjects ingesting a liquid beverage (per kilogram body mass: 0.33g of Whey Protein Concentrate dissolved in water ) prior to completion of a prescribed resistance exercise training (RET) session.
Muscle Contractile Function to be conducted prior to and following the RET session by laboratory-based ergometry. Muscle Protein Synthesis induced by RET to be measured by deuterium incorporation in to skeletal muscle sampled by microbiopsy.
干预措施: Whey Protein Concentrate (Dietary Supplement)
结局指标
主要结局
Change in Muscle Contractile Function
时间窗: Day 9, 10, 11, 12, 13, 14, 15, 16 and 17
Maximal Voluntary Contract (MVC) of Knee Extensor Muscle measured by laboratory-based ergometry
次要结局
- Change in Muscle Protein Synthesis(Day 11 and 16)