One Year of Velocity-based Resistance Training in Older People Living in Nursing Homes: Effects on Skeletal Muscle Mass, Muscle Function, and Physical and Cognitive Function
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Change in muscle power
研究概览
简要总结
This study is an exercise intervention assessing the efficacy of a velocity-based resistance training (VBRT) in institutionalized older adults.
The aim of this study is to assess the effects of one year of velocity-based resistance training on skeletal muscle mass, muscle function, and physical and cognitive function in older adults living in nursing homes.
详细描述
Evidence supports the fact that resistance exercise training is effective in improving old adult's health and palliate age-related disorders. New approaches in resistance training are emerging to maximize monitoring control, providing more tailored and potentially more effective exercise interventions. Among them, the velocity-based resistance training (VBRT) is being established in healthy populations or populations with pathologies. However, the effects of long-term VBRT in institutionalized older adults are still unknown.
Thus, the aim of this study is to assess the effects of one year of velocity-based resistance training on skeletal muscle mass, muscle function, and physical and cognitive function in older adults living in nursing homes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Older people living permanently in nursing home.
- •Age ≥ 65 years old.
- •Are able to walk with/without assistance.
- •Have ability to communicate with the research team.
排除标准
- •Terminal illness.
- •Any illness not controled (cardiac, pulmonary, etc).
- •If there is a risk of bone fracture according to medical staff.
结局指标
主要结局
Change in muscle power
时间窗: T0 (baseline); T1 (post 6 weeks); T2 (post 12 weeks); T3 (post 23 weeks) and T4 (post 39 weeks).
Muscle power assessed in leg press machine and sit to stand test.
Changes in neuromuscular performance of lower-body
时间窗: T0 (baseline); T1 (post 6 weeks); T2 (post 12 weeks); T3 (post 23 weeks) and T4 (post 39 weeks).
Change in the force-velocity relationship in leg press exercise.
次要结局
- Change in physical function based on the Short Physical Performance Battery score(T0 (baseline); T1 (post 6 weeks); T2 (post 12 weeks); T3 (post 23 weeks) and T4 (post 39 weeks).)
- Change in frailty (score) using Fried's Frailty Criteria and Frailty Trait Scale - Short Form(T0 (baseline); T1 (post 6 weeks); T2 (post 12 weeks); T3 (post 23 weeks) and T4 (post 39 weeks).)
- Change in muscle mass using ultrasonography.(T0 (baseline); T1 (post 6 weeks); T2 (post 12 weeks); T3 (post 23 weeks) and T4 (post 39 weeks).)
- Change in disability using Barthel and Lawton scales(T0 (baseline); T1 (post 6 weeks); T2 (post 12 weeks); T3 (post 23 weeks) and T4 (post 39 weeks).)
- Change in cognitive function using Mini-Mental State Examination(T0 (baseline); T1 (post 6 weeks); T2 (post 12 weeks); T3 (post 23 weeks) and T4 (post 39 weeks).)
- Change in handgrip strength(T0 (baseline); T1 (post 6 weeks); T2 (post 12 weeks); T3 (post 23 weeks) and T4 (post 39 weeks).)
研究者
Julián Alcázar Caminero
PhD, Associate Professor
University of Castilla-La Mancha