Comparsion of IV Dexmedetomidine, Tramdol and Ketamine for Post Spinal Anesthesia Shivering.

Phase 3

• Conditions: Post-Surgical Complication
• Interventions: Drug: Dexmedetomidine; Drug: Ketamine; Drug: Tramadol

• Registration Number: NCT05311722
• Lead Sponsor: Sheikh Zayed Medical College

Brief Summary

To study control of post spinal shivering in patients undergoing lower segment cesarean section using dexmedetomidine, tramadol and ketamine

Detailed Description

Its a Comparison of drugs for a better control of post spinal shivering in patietns underwent cesarean section.using grades of shivering (0-4)patients will be assessed

Study Timeline

• Status Verified: 2022-03
• Study First Submitted: 2022-03-09
• Study First Submitted QC: 2022-04-04
• Last Update Submitted: 2022-04-04
• Study First Posted: 2022-04-05
• Last Update Posted: 2022-04-05
• Study Start: 2022-04-30
• Primary Completion: 2022-12-31
• Study Completion: 2023-02-20

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 71

Inclusion Criteria

• Woman of age 18-60
• Pregnant woman in outdoor patient department and emergency

Exclusion Criteria

• patient. with history of hypersensitivity to opioids,
• ketamine or bupivacaine
• History of cardiovascular disease,
• Hypertension,
• psychosis,
• antepartum hemorrhage,
• cord prolapse,
• fetal distress

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Dexmedetomidine	Dexmedetomidine	Inj.dexmedetomidine 0.5mcg/kg diluted in 10ml N/s given as iv infusion over 10 minutes
Ketamine	Ketamine	Inj.ketamine 0.5mg/kg diluted in 10ml N/s given as iv infusion over 10 minutes
Tramadol	Tramadol	Inj.tramadol 0.5mg/kg diluted in 10ml N/s given as iv infusion over 10 minutes

Primary Outcome Measures

Name	Time	Method
Assessment of post spinal shivering by observing grades of shivering	10 minutes	Control of post spinal shivering dexmedetomidine, tramadol and ketamine for control of post spinal shivering.