Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is consider...
Tramadol is approved for the management of moderate to severe pain in adults.
Tramadol is also used off-label in the treatment of premature ejaculation.
Medina Medical Center, Medina, Saudi Arabia
West China Hospital, Sichuan University, Chengdu, Sichuan, China
Liaquat National Hospital and Medical College, Karachi, Sindh, Pakistan
Istanbul University-Cerrahpasa, Istanbul, Fatih, Turkey
Aalborg University Hospital, Aalborg, Denmark
The Cleveland Clinic Florida, Coral Springs, Florida, United States
The Cleveland Clinic Ohio, Avon, Ohio, United States
Penn Highlands Dubois, DuBois, Pennsylvania, United States
Aalborg University Hospital, Aalborg, Denmark
University Hospital Of Larissa, Larissa, Thessaly, Greece
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