Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is consider...
Tramadol is approved for the management of moderate to severe pain in adults.
Tramadol is also used off-label in the treatment of premature ejaculation.
Corporació Sanitària Parc Taulí, Sabadell, Barcelona, Spain
Assiut University, Assiut, Egypt
Dept. of Anaesthesiology and Intensive Care Medicine, Medical University of Graz, Graz, Austria
Affiliated Cancer Hospital of Shantou University Medical College Medical, Shantou, Guangdong, China
Wake Forest Health Sciences, Winston-Salem, North Carolina, United States
Madiha Ahmed, Islamabad, Pakistan
Department of Pediatrics, Rawalpindi, Punjab, Pakistan
Emory University Orthopaedic and Spine Hospital, Atlanta, Georgia, United States
Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey
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