The effect of sitagliptin and metformin on the quality of oocyte and embryos, the number of retrieved oocyte

Phase 3

Completed

• Conditions: Polycystic ovarian syndrome.; Polycystic ovarian syndrome; E28.2

• Registration Number: IRCT20220803055607N1
• Lead Sponsor: Babol University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 76

Inclusion Criteria

Diagnosis of Polycystic ovary syndrome (PCOS) based on Rotterdam criteria
Age 18 to 40 years
BMI=20
Insulin resistant
In vitro fertilization (IVF) candidate
Not taking drugs that are effective on the activity of two drugs at this time in the last 3 months
Not taking weight-loss drugs or having any slimming diet or regular aerobic exercise in the last 3 months
Not receiving assisted reproductive treatments in the last 3 months

Exclusion Criteria

Getting pregnant during the study
The patient's lack of consent to enter or the patient's lack of cooperation in taking the medicine
smoking

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Oocyte and embryo quality. Timepoint: Two months after the start of the intervention. Method of measurement: The average number of retrieved oocyte, fertilized and formed embryos with excellent quality.