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Clinical Trials/CTRI/2024/07/070030
CTRI/2024/07/070030Not yet recruitingNot Applicable

Study of pattern of clinical presentation and management of skin and soft tissue infection in a tertiary care rural hospital in India

Dr Deepanshu Sharma1 site in 1 country80 target enrollmentStarted: July 24, 2024Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
80
Locations
1
Primary Endpoint
clinical presentation of skin and soft tissue infection

Study Overview

Brief Summary

Skin and Soft-tissue infections are frequent, usually mild to moderate in intensity, and

easily treated with a range of medications.Common simple SSTIs include

cellulitis, folliculitis, furuncles, carbuncles, abscesses, and trauma-related

infections that are generally easily treatable. Complicated infections extending into

and involving the underlying deep tissues include deep abscesses, decubitus ulcers,

necrotising fasciitis, Fournier gangrene, and infections from human or animal bites.

Most simple SSTIs resolve automatically.Large, complex, and painful SSTIs

require medical attention.Depending on the severity of the infection, they may need

antibiotics, suction with a syringe, incision and drainage (I/D), debridement and

drainage (D/D), amputation or even surgery may be required

Diagnosis of these infections is mostly clinical. Guidelines suggest that CBC and

wound culture should be ordered for all complicated SSTIs, and for those with sepsis

should be ordered for blood culture as well . These tests can be avoided in

uncomplicated infections.

Necrotising soft-tissue infections , or NSTIs, are extremely deadly. The degree of

organ system failure at the time of admission, age, length of infection, delayed initial

debridement, and decreased renal function are among the risk factors for death in

these cases. Treating patients with NSTI can sometimes be most challenging when it

comes to establishing the diagnosis, and early and accurate diagnosis depends onamputations are performed on diabetic patients, with chronic DFU being one of the

most common reasons for hospitalisation in this population.

Mono-microbial infections are mainly caused by haemolytic Group A Streptococcus,

Staphylococcus aureus, or clostridial species[7]. Younger people and the extremities

are affected by group A streptococcal infections, which are linked to a streptococcal

toxic shock-like syndrome.

In order to assist clinicians in determining the severity of an infection, a number of

classification methods and algorithms have been presented. Nonetheless, the majority

of clinical evaluations have been derived from either retrospective research or the

author’s personal "clinical experience," highlighting the necessity of conducting

prospective studies that include outcomes and management considerations in addition

to established severity levels.

We try to assess all the clinical circumstances related to soft-tissue infections in this

study, including the prognosis, therapy and their management outcomes.

Study Design

Study Type
Observational

Eligibility Criteria

Ages
0.00 Year(s) to 70.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • All patients presenting with skin and soft tissue infections of any gender.
  • Patients above 18 years of age with or without comorbidities.
  • Patient less than 18 years of age referred to the Department of surgery Patients with infection of any etiology.

Exclusion Criteria

  • Patient not willing to participate in the study .
  • Patient on steroids Patients with malignancy HHH positive patients Pregnant females Patients with psychiatric illness.

Outcomes

Primary Outcomes

clinical presentation of skin and soft tissue infection

Time Frame: 16-34 months

Secondary Outcomes

  • management outcome of skin and soft tissue infection(16-34 months)

Investigators

Sponsor
Dr Deepanshu Sharma
Sponsor Class
Other [self]
Responsible Party
Principal Investigator
Principal Investigator

Dr Deepanshu Sharma

Datta Meghe Institute of Higher Education and Research

Study Sites (1)

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