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Clinical Trials/NCT03490747
NCT03490747
Completed
Not Applicable

Clinical and Cost-effectiveness of a Co-developed, Evidence-based Physical Activity Referral Scheme for the Treatment and Prevention of Health Conditions: a Pragmatic Trial

Paula Watson1 site in 1 country68 target enrollmentMarch 12, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiovascular Risk Factor
Sponsor
Paula Watson
Enrollment
68
Locations
1
Primary Endpoint
Change in cardiorespiratory fitness
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The study will evaluate the effectiveness of a co-developed exercise referral scheme. Participants will be recruited to one of three groups 1. Co-developed exercise referral scheme, 2. Usual care exercise referral scheme, 3. No treatment control (no intervention). The study will measure effectiveness by observing change in cardiorespiratory fitness at 12 weeks. Intervention cost-effectiveness will also be evaluated at 3 months follow-up using objective physical activity data.

Detailed Description

Evidence of effectiveness for UK exercise referral is unclear. This representation has been deemed an unfair assessment of its potential to impact public health. This is due to systematic review evidence that reports evaluations of exercise referral interventions that are not evidence-based or underpinned by behaviour change theory. This evaluation is the third phase of a project that aims to co-develop (Phase 1), pilot (phase 2) and evaluate (phase 3) an evidence-based exercise referral scheme. This approach is underpinned by the Medical Research Council guidance for complex interventions. Through co-development work with a multidisciplinary group of researchers and local stakeholders and subsequent pilot work, it is hypothesised that the co-developed, evidence-based intervention will have improved chances of implementation success, and therefore, clinical effectiveness.

Registry
clinicaltrials.gov
Start Date
March 12, 2018
End Date
February 28, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Sponsor
Paula Watson
Responsible Party
Sponsor Investigator
Principal Investigator

Paula Watson

Senior Lecturer

Liverpool John Moores University

Eligibility Criteria

Inclusion Criteria

  • 18 years or older and have a health-related risk factor (e.g. high blood pressure, hyperglycaemia, obesity etc.) or a health condition (diabetes, cardiovascular disease, anxiety, depression etc.) that may be alleviated by increasing current PA levels.

Exclusion Criteria

  • Uncontrolled health-conditions (Cardiac, metabolic, respiratory etc.) and/or any recent traumatic events (e.g. myocardial infarction).
  • Unstable angina or aortic stenosis.
  • Severe psychological or neurological conditions.
  • Participation in an ERS at any location other than the research centres (at the time of recruitment).

Outcomes

Primary Outcomes

Change in cardiorespiratory fitness

Time Frame: Baseline and week 12.

Estimated via the Astrand-Rhyming cycle protocol using the updated age and sex specific nomogram.

Secondary Outcomes

  • Change in psychological wellbeing(Baseline, week 12, and 6 months.)
  • Change in triglycerides(Baseline and week 12.)
  • Change in objective physical activity levels(Baseline, week 12, and 6 months)
  • Change in total cholesterol(Baseline and week 12.)
  • Change in plasma glucose(Baseline and week 12.)
  • Change in flow-mediated dilation(Baseline and week 12.)
  • Attendance at consultations(Week 1, 4, 8, 12, and 18)
  • Attendance at fitness centre(Week 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12. Months 4, 5 and 6)
  • Fidelity - consultation attendance(Week 18)
  • Change in carotid vasoreactivity(Baseline and week 12.)
  • Fidelity - consultation communication strategies(Week 1, 4, 8, 12, and 18)
  • Change in health-related quality of life measure(Baseline, week 12, and 6 months.)
  • Loss in revenue costs(Week 18)
  • Change in self-reported physical activity(Baseline, week 12, and 6 months.)
  • Change in patient health care utilisation costs(Baseline and 6 months)
  • Intervention operating and set up costs(Week 18)
  • Change in patient costs(Baseline, Week 12 and 6 months)

Study Sites (1)

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