Randomized comparison of Magnesium and Dexmedetomodine as adjuvant to Ropivacaine in pediatric caudal block

Phase 3

Not yet recruiting

Conditions: Other external cause status,

Registration Number: CTRI/2020/05/025409

Lead Sponsor: Government medical college jammu

Brief Summary: After preanesthetic checkup, the children shall be randomly allocated in 3 groups of 20 patients each receiving 0.2% Ropivacaine 0.75ml/kg caudally with following adjuvants:

Group C (control), Group MG (magnesium), Group D (dexmedetomidine)

Parameters to be observed are Post op duration of analgesia , sedation score and any adverse effects if any.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

ASA group I or II in age group of 1-10 years, of either sex, , undergoing elective lower abdominal surgeries under general anaesthesia with caudal block supplementation.

Exclusion Criteria

ASA III or more, consent refusal, known allergy to study drugs, any coagulation abnormalities,prolonged surgery (>90min),any intensive need for preop sedation or analgesia, any contraindication to neuraxial blockade (infection,anatomic or neurological abnormality,heart disease,any muscular disorder), use of any medication that affect neurological system.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of analgesia and need for rescue analgesia	At baseline, at end of surgery , 1 hour after surgery 4 hours after surgery up to next 24 hrs

Secondary Outcome Measures

Name	Time	Method
Sedation score and adverse effects if any	At baseline, at end of surgery , 1 hour after surgery 4 hours after surgery up to next 24 hrs

Trial Locations

Locations (1): Government medical college jammu
🇮🇳
JAMMU, & KASHMIR, India
Government medical college jammu
🇮🇳JAMMU, & KASHMIR, India
Dr Megha Gandotra
Principal investigator
9469163365
megha.gandotra89@gmail.com