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临床试验/NCT02288780
NCT02288780终止不适用

Transthoracic Echocardiographic Evaluation of the Cardiac Function During Transurethral Resection of Prostate in Elderly Patients

Yonsei University0 个研究点目标入组 2 人开始时间: 2014年12月最近更新:
适应症

试验速览

阶段
不适用
状态
终止
入组人数
2
主要终点
diastolic function by TTE

研究概览

简要总结

Transurethral resection of the prostate (TURP) is a standard surgical treatment for benign prostatic hyperplasia (BPH). Non-conductive irrigation fluid is used to maintain good visibility of the operating field during resection of the prostate. Absorption of this hypotonic solution into the bloodstream can cause fluid overload and dilutional hyponatremia, resulting in adverse cardiovascular and central nervous system effects, transurethral resection (TUR) syndrome. BPH is common in elderly men above 60 years old. These aged people commonly have diastolic impairment by normal physiologic change without consistent symptom. This study aimed to evaluate the cardiac function focused mainly diastolic function during TURP with transthoracic echocardiography. Also, we will focus the effets of amount of irrgation fluid on left ventricular diastolic function in patients with pre-existing diastolic dysfunction.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
65 Years 至 85 Years(Older Adult)
性别
Male
接受健康志愿者

入选标准

  • Above 65years of age
  • American Society of Anesthesiologists (ASA) Physical Status I, II, III.
  • undergoing transurethral resection of the prostate(TURP)"

排除标准

  • severe coagulopathy or bleeding disorder(platelet count<75000, PT INR >1.2)
  • short stature (under 150 cm)
  • underwent coronary artery bypass graft
  • contraindications of regional anesthesia "

结局指标

主要结局

diastolic function by TTE

时间窗: The participants will be followed for the duration of surgery (TURP), an expected average of 1 hour.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

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