Transthoracic Echocardiographic Evaluation of the Cardiac Function During Transurethral Resection of Prostate in Elderly Patients
- Conditions
- BPH
- Registration Number
- NCT02288780
- Lead Sponsor
- Yonsei University
- Brief Summary
Transurethral resection of the prostate (TURP) is a standard surgical treatment for benign prostatic hyperplasia (BPH). Non-conductive irrigation fluid is used to maintain good visibility of the operating field during resection of the prostate. Absorption of this hypotonic solution into the bloodstream can cause fluid overload and dilutional hyponatremia, resulting in adverse cardiovascular and central nervous system effects, transurethral resection (TUR) syndrome. BPH is common in elderly men above 60 years old. These aged people commonly have diastolic impairment by normal physiologic change without consistent symptom. This study aimed to evaluate the cardiac function focused mainly diastolic function during TURP with transthoracic echocardiography. Also, we will focus the effets of amount of irrgation fluid on left ventricular diastolic function in patients with pre-existing diastolic dysfunction.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- Male
- Target Recruitment
- 2
- Above 65years of age
- American Society of Anesthesiologists (ASA) Physical Status I, II, III.
- undergoing transurethral resection of the prostate(TURP)"
- severe coagulopathy or bleeding disorder(platelet count<75000, PT INR >1.2)
- short stature (under 150 cm)
- underwent coronary artery bypass graft
- contraindications of regional anesthesia "
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method diastolic function by TTE The participants will be followed for the duration of surgery (TURP), an expected average of 1 hour.
- Secondary Outcome Measures
Name Time Method