Transthoracic Echocardiographic Evaluation of the Cardiac Function During Transurethral Resection of Prostate in Elderly Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- BPH
- Sponsor
- Yonsei University
- Enrollment
- 2
- Primary Endpoint
- diastolic function by TTE
- Status
- Terminated
- Last Updated
- 7 years ago
Overview
Brief Summary
Transurethral resection of the prostate (TURP) is a standard surgical treatment for benign prostatic hyperplasia (BPH). Non-conductive irrigation fluid is used to maintain good visibility of the operating field during resection of the prostate. Absorption of this hypotonic solution into the bloodstream can cause fluid overload and dilutional hyponatremia, resulting in adverse cardiovascular and central nervous system effects, transurethral resection (TUR) syndrome. BPH is common in elderly men above 60 years old. These aged people commonly have diastolic impairment by normal physiologic change without consistent symptom. This study aimed to evaluate the cardiac function focused mainly diastolic function during TURP with transthoracic echocardiography. Also, we will focus the effets of amount of irrgation fluid on left ventricular diastolic function in patients with pre-existing diastolic dysfunction.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Above 65years of age
- •American Society of Anesthesiologists (ASA) Physical Status I, II, III.
- •undergoing transurethral resection of the prostate(TURP)"
Exclusion Criteria
- •severe coagulopathy or bleeding disorder(platelet count\<75000, PT INR \>1.2)
- •short stature (under 150 cm)
- •underwent coronary artery bypass graft
- •contraindications of regional anesthesia "
Outcomes
Primary Outcomes
diastolic function by TTE
Time Frame: The participants will be followed for the duration of surgery (TURP), an expected average of 1 hour.