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Clinical Trials/NCT02288780
NCT02288780
Terminated
Not Applicable

Transthoracic Echocardiographic Evaluation of the Cardiac Function During Transurethral Resection of Prostate in Elderly Patients

Yonsei University0 sites2 target enrollmentDecember 2014
ConditionsBPH

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
BPH
Sponsor
Yonsei University
Enrollment
2
Primary Endpoint
diastolic function by TTE
Status
Terminated
Last Updated
7 years ago

Overview

Brief Summary

Transurethral resection of the prostate (TURP) is a standard surgical treatment for benign prostatic hyperplasia (BPH). Non-conductive irrigation fluid is used to maintain good visibility of the operating field during resection of the prostate. Absorption of this hypotonic solution into the bloodstream can cause fluid overload and dilutional hyponatremia, resulting in adverse cardiovascular and central nervous system effects, transurethral resection (TUR) syndrome. BPH is common in elderly men above 60 years old. These aged people commonly have diastolic impairment by normal physiologic change without consistent symptom. This study aimed to evaluate the cardiac function focused mainly diastolic function during TURP with transthoracic echocardiography. Also, we will focus the effets of amount of irrgation fluid on left ventricular diastolic function in patients with pre-existing diastolic dysfunction.

Registry
clinicaltrials.gov
Start Date
December 2014
End Date
May 1, 2015
Last Updated
7 years ago
Study Type
Observational
Sex
Male

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Above 65years of age
  • American Society of Anesthesiologists (ASA) Physical Status I, II, III.
  • undergoing transurethral resection of the prostate(TURP)"

Exclusion Criteria

  • severe coagulopathy or bleeding disorder(platelet count\<75000, PT INR \>1.2)
  • short stature (under 150 cm)
  • underwent coronary artery bypass graft
  • contraindications of regional anesthesia "

Outcomes

Primary Outcomes

diastolic function by TTE

Time Frame: The participants will be followed for the duration of surgery (TURP), an expected average of 1 hour.

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