Registry of Biological Samples, Clinical Information and Epidemiological Data of COVID-19 Patients Admitted at the University Hospital of Verona (AOUI Verona)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 430
- 试验地点
- 1
- 主要终点
- Arterial blood gas anaysis pH in COVID-19 patients admitted to University Hospital of Verona
研究概览
简要总结
The registry of COVID-19 patients was designed to collect epidemiolgical, demographic, clinical, anamnestic and outcome information together with serological and microbiological samples from COVID-19 patients admitted at the University Hospital of Verona (Azienda Ospedaliera Universitaria Integrata, AOUI Verona). All SARS-CoV 2 positive patients admitted and able to give an informed consent are included, irrespectively of age and gender.
详细描述
Anamnestic data are collected at the enrollment, while all the other clinical and epidemiological information are retrieved retrospectively from patients' medical records and electronic health records.
Serological and microbiological samples (blood samples, fecal samples and nasal/rectal swabs) are collected within 48 hours after admission and during the hospital stay, according with routine internal procedures.The biological samples are stored at the University Laboratory for Medical Research (Laboratorio Universitario di Ricerca Medica, LURM).
A dedicated database has been created and implemented to collect all the above mentioned information.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •PCR for SARS-CoV 2 positive on NPS swab or high suspicion of SARS-CoV 2 with ongoing swab;
- •All ages;
- •All genders;
- •Informed consent obtained.
排除标准
- •Failure to obtain the informed consent.
结局指标
主要结局
Arterial blood gas anaysis pH in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
pH
Blood pressure (mmHg) on admission in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
Blood pressure (mmHg)
Respiratory rate (breaths per minute) on admission in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
Pulse rate (beats per minute)
Peripheral oxygen saturation (%) on admission in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
Peripheral oxygen saturation (%)
Body temperature (°C) on admission in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
Body temperature (°C)
Lymphocytes (cell/mm3) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
Lymphocytes (cell/mm3)
L-lattato deidrogenasi (LDH, mU/ml) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
LDH (mU/ml)
Creatine kinase (CK, U/L) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
CK (U/L)
Epidemiological predictors of poor outcomes in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
Epidemiological data including demographic data, contact with COVD-19 positive patients and onset of symptoms.
C reactive protein (CRP, m/gL) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
CRP (m/gL)
Clinical predictors of poor outcomes in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
Underlying chronic diseases, signs/symptoms related with COVID-19 diseases an clinical presentation on admission
Pulse rate (beats per minute) on admission in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
Pulse rate (beats per minute)
Platelets (cell/mm3) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
Platelets (cell/mm3)
D-dimer (μg/L) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
D-dimer (μg/L)
ferritin (mcg/L) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
ferritin (mcg/L)
Creatinine (mg/dl) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
Creatinine (mg/dl)
Procalcitonin (PCT, ng/mL) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
PCT (ng/mL
Neutrophils (cell/mm3) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
Neutrophils (cell/mm3)
AST (U/L) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
AST (U/L)
Arterial blood gas anaysis HCO3 (mmol/l) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
HCO3 (mmol/l)
White Blood Count (WBC, cell/mm3) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
White Blood Count (WBC, cell/mm3)
fibrinogen (g/L) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
fibrinogen (g/L)
ALT (U/L) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
ALT (U/L)
Arterial blood gas anaysis pO2 (mmHg) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
pO2 (mmHg)
Virological factors associated with the pathogenesis of COVID-19
时间窗: through study completion, an average of 3 months
Nasal and rectal swabs, fecal samples and blood samples
Arterial blood gas anaysis pCO2 (mmHg) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
pCO2 (mmHg)
Arterial blood gas anaysis SpO2 (%) in COVID-19 patients admitted to University Hospital of Verona
时间窗: through study completion, an average of 3 months
SpO2 (%)
Host-related factors associated with the pathogenesis of COVID-19
时间窗: through study completion, an average of 3 months
IL-6 (pg/mL)
次要结局
未报告次要终点
研究者
Evelina Tacconelli
Professor
Azienda Ospedaliera Universitaria Integrata Verona