A clinical trial to study the effect of Haridradi taila janubasti in knee osteoarthritis.

Not yet recruiting

• Conditions: Bilateral primary osteoarthritis of knee. Ayurveda Condition: SANDHIGATAVATAH,

• Registration Number: CTRI/2025/05/086288
• Lead Sponsor: Dr Neha Mukund Bagul

Brief Summary

The population based study from India shows prevalence of Janusandhigata vata is 15%. It is one of the disease which is painful and affects normal routine of life.So there is a need to find an alternative solution of this problem .Present study of randomized controlled trial will be carried out to study the

efficacy of Haridradi taila janubasti in Janusandhigata vata with special reference to knee osteoarthritis. For present

study subjects between age group 45-80 years will be taken irrespective of the religion ,gender,socioeconomic status. Total sample size taken is 66 and  patients will be taken for the study with 33 patients in Group A(trial group) and 33 patients in Group B(control group). Haridradi taila janubasti is taken in group A(trial group) and Nirgundi taila janubasti is taken for Group B(control group). Procedure will be done with external application for 7 days and follow up will be taken on 14th day .All SOP will be followed. All the findings will be entered in case record form .Observations will be drawn before, during and after treatment .Result will be drawn with the help of statistical method.Discussion will be done on the basis of observations. Summary will be drawn .Conclusion will be drawn strictly on basis of statistical analysis and will be unbiased.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-02-05
• Study Start: 2025-05-16

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

• 1)Patient aged between 45-80 years irrespective of gender and religion 2)Persistent knee joint pain which worsens with use and morning stiffness present which lasts not more than 2 hours.
• 3)Patients presenting any 2 or more classical signs and symptoms ofJanusandhigata vata that is Janu Sandhishool,Shotha, Sphutana, Sparshasahavta, Sthambhata, Aakunchana Prasarana vedana.

Exclusion Criteria

1)Patient with K/C/O HIV, TB,DM, neurological disorders,any skindiseases, severe present injury ,fractures or dislocation,bone tumours of knee joint 2)Patients who have taken corticosteriodal injections before 3 months of trial 3)Patients who have metallic implant in knee joint or with TKR 4)Patients with anatomical defect and who needs surgical intervention.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1)To access the effect of Haridradi taila Janubasti for 7 days in signs and symptoms of Janusandhigatavata by comparison of the score of clinical evaluation.	0th,7th and 14th day

Secondary Outcome Measures

Name	Time	Method
Where the trial group stands in comparison to control group in reduction of signs and symptoms of janusandhigata vata	18 months

Trial Locations

Locations (1)

SMBT Ayurved college and hospital; 🇮🇳 Nashik, MAHARASHTRA, India

SMBT Ayurved college and hospital

🇮🇳Nashik, MAHARASHTRA, India

Dr Neha Mukund Bagul

Principal investigator

9209295475

bagulneha2599@gmail.com