The effect of intermittent inflation of an arm tourniquet (remote ischaemic preconditioning) on patient outcomes after surgery for intra-abdominal cancer (RIPCa) - a pilot study

Not Applicable

Completed

• Conditions: Elective surgery for intra-abdominal cancer; Surgery

• Registration Number: ISRCTN11439947
• Lead Sponsor: Royal Surrey County Hospital

Brief Summary

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35407378/ (added 18/07/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-11-30
• Study Start: 2021-10-26
• Last Update Posted: 20 June 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 47

Inclusion Criteria

Adults 18 years or over undergoing elective surgery for intra-abdominal cancer (colorectal, pancreatic or gynaecological) under general anaesthesia, and at increased risk of postoperative complications, as defined by the American College of Surgeons National Surgical Quality Improvement Project (ACS NSQIP) calculated risk of morbidity >10%

Exclusion Criteria

1. Patients unable to give consent
2. Day surgery
3. Emergency surgery
4. Total intravenous anaesthesia
5. Pregnancy
6. Recent (< 1 month) or ongoing acute myocardial infarction
7. Unstable or ongoing angina
8. Peripheral vascular disease
9. History of vascular intervention in the limb to be used for RIPC
10. Thromboembolic disease
11. Significant coagulopathy or bleeding diathesis
12. Sickle cell disease
13. Neuromuscular diseases
14. Use of sulfonylureas or nicorandil

Study & Design

• Study Type: Interventional
• Study Design: Not specified