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Effects of estrogen on prognosis of patient with diffuse axonal injury due to severe traumatic brain injury

Phase 2
Conditions
Diffuse axonal injury.
Diffuse brain injury
Registration Number
IRCT2014091919227N1
Lead Sponsor
Vice chanscellor for research, Tabriz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Male
Target Recruitment
Not specified
Inclusion Criteria

Men 15 to 70 years; Diffuse axonal injury diagnosis; GCS less than or equal to 8; Hospitalization in less than 8 hours of after trauma; Having informed consent to participate in the study; Lack of talent to thromboembolism.

Exclusion criteria:
Sex woman; Patients with refractory seizure; History of deep vein thrombosis or infection; Any history of head trauma; Any history of brain procedure; History of ischemic lesions and hemorrhagic stroke; People prone to pulmonary thromboembolism and deep vein thrombosis; (a) smoking; (b) a family history of deep vein thrombosis and pulmonary thromboembolism; (c) heart failure; (d) inflammatory bowel disease (ulcerative colitis); (e) a history of cancer; (f) hereditary disorders are prone to blood clots

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
evel of consciousness. Timepoint: Admission time, discharge time and three months after discharge. Method of measurement: Glasgow coma scale.
Secondary Outcome Measures
NameTimeMethod
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