The modified Atkins diet in patients with refractory epilepsy and severe intellectual disability: a randomized controlled trial. - The modified Atkins diet in epilepsy: an RCT.

Tergooiziekenhuizen0 个研究点目标入组 29 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•Age > 18 years, moderate to severe ID;
•Refractory epilepsy, defined as failure of two tolerated and appropriately chosen and used AED schedules;
•More than two seizures per month, which are judged by the carers and the treating physician to impose a significant impact on the patients* QOL --justifying treatment;
•Informed consent obtained by at least one legal representative;

•Undergone epilepsy surgery in the last 6 months, or awaiting pre-surgical evaluation;
•Underwent implantation of a vagal nerve stimulation in the last 6 months;
•Previous use of the MAD or the KD for more than 7 days in the last year prior to inclusion;
•Hypercholesterolemia (total cholesterol >8), cardiovascular disease or kidney failure, metabolic disorders known to deteriorate after fasting;
•Severe underweight, defined as a BMI < 16.5;
•Diabetes Mellitus.

发起方

Tergooiziekenhuizen