Pre-dinner vs. Post-dinner Exercise on Glycemic Control

Not Applicable

Completed

• Conditions: Type 2 Diabetes
• Interventions: Other: No exercise; Other: exercise then meal; Other: Meal then exercise

• Registration Number: NCT02180620
• Lead Sponsor: University of Missouri-Columbia

Brief Summary

With many medications we prescribe them relative to time of day or a meal. This study established if pre dinner vs post dinner exercise was more effective at altering post dinner glucose and triglyceride levels vs no exercise at all.

Detailed Description

All participants completed three trials in a random order in which they consumed a standardized dinner meal with 1) no RE (NoRE), 2) pre-dinner RE (RE→M), and 3) post-dinner RE beginning 45 min after dinner (M→RE). Diet was standardized during the day of testing. Participants reported to the lab for testing sometime between 3 - 5:30 p.m. and upon arrival a venous catheter was inserted into a forearm vein. Frequent blood sampling, indirect calorimetry measurements, and subjective well-being measurements ensued for \~5.75 h while the participants were in the lab.

Study Timeline

• Study Start: 2013-09
• Primary Completion: 2014-04
• Study Completion: 2014-04
• Study First Submitted: 2014-06-30
• Study First Submitted QC: 2014-07-01
• Study First Posted: 2014-07-02
• Status Verified: 2017-06
• Last Update Submitted: 2017-06-06
• Last Update Posted: 2017-06-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 13

Inclusion Criteria

• Obese ( body mass index 30-45 kg/m2)
• Physician diagnosed with type 2 diabetes receiving standard medical care
• Non-smokers
• Pregnancy
• Lactating mothers

Exclusion Criteria

• Insulin
• Surgical weight loss
• Orthopedic limitations to exercise
• Weight loss in the previous 3 months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
No exercise	No exercise	participants will remain sedentary during testing
exercise then meal	exercise then meal	45 min of resistance training will be performed prior to a standard meal
Meal then exercise	Meal then exercise	45 min of resistance training will be performed after a standard meal

Primary Outcome Measures

Name	Time	Method
glucose concentrations	Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h

Secondary Outcome Measures

Name	Time	Method
triglyceride concentrations	Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h