Assessing the impact of exercise timing on glycaemic control

Not Applicable

Recruiting

• Conditions: Type 2 Diabetes Mellitus; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12619000072112
• Lead Sponsor: Murdoch University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-01-18
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Non-smoking, sedentary (defined as the accrual of less than 150 min of exercise per week) individuals who are overweight (body mass index more than or equal to 27 kg/m2) and have an existing diagnosis of Type 2 diabetes mellitus

Exclusion Criteria

Participants will not be eligible if: (i) they are unable to complete exercise or have a condition which is known to be aggravated by exercise (assessed using the Exercise and Sports Science Australia pre-exercise screening tool); (ii) they are on insulin; (iii) have had surgery for weight loss; (iv) they had prior history of heart, lung, kidney, endocrine or liver disease; (v) experienced recent weight loss (4 kg or more) in previous month.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome will be glycaemic control as done through the analysis of composite measures that include: glycosylated haemoglobin (HbA1c),fasting glucose and 1,5-anhydroglucitol (1,5-AG) levels. Blood samples will be sent to an external provider (Western Diagnostic) for the analysis of HbA1c and 1,5-AG. Additionally,blood samples will be analysed in-house using a COBAS 6000 chemistry analyzer for fasting glucose levels.[Glycosylated haemoglobin, fasting glucose and 1,5-AG levels will be done prior to the start of the 12-week training intervention during baseline assessment (study day) and at least 24 hours after the last training session in week 12, but no more than 96 hours after the last training session (post-intervention study day). In addition, fasting glucose and 1,5-AG levels will be done during the mid-intervention assessments which will occur in week 6.]