Mechanisms of Implant Failure during Aseptic Loosening of Hip and Knee Endoprotheses (Cell biology of aseptic implant loss)
Not Applicable
Recruiting
- Conditions
- M16M17Coxarthrosis [arthrosis of hip]Gonarthrosis [arthrosis of knee]
- Registration Number
- DRKS00032796
- Lead Sponsor
- Medizinische Hochschule Hannover
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Patients with coxarthrosis who have a total hip arthroplasty implanted
- Patients with gonarthrosis who are implanted with a total knee arthroplasty
- Patients with revision surgery on the hip due to implant loosening
- Patients with revision surgery on the knee due to implant loosening
Exclusion Criteria
- Detection of infections with hepatitis viruses, MRSA
- Known depression
- Heavy smokers
- Patients with positive tumor history
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary goal is to characterize cell populations and their molecular composition in the lo-cal and systemic tissue response (host response) in the context of hip and knee implants.
- Secondary Outcome Measures
Name Time Method not applicable