ISRCTN11220163
Completed
未知
Improving outcome measures for physiotherapy trials of airway clearance in adults with cystic fibrosis
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Cystic fibrosis
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
- Enrollment
- 68
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/33020113/ protocol (added 08/10/2020) 2022 Abstract results in https://doi.org/10.1016/S1569-1993(22)00848-7 Presented at North American Cystic Fibrosis Conference (added 01/08/2023)
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Diagnosis of Cystic Fibrosis (confirmed by standard criteria)
- •2\. Aged 16 years or over
- •3\. Registered as patients of the Royal Brompton Hospital
Exclusion Criteria
- •1\. Evidence of pulmonary exacerbation within 3 weeks prior to screening
- •2\. Any change in a chronic treatment/prophylaxis regimen for CF or CF\-related condition within 4 weeks of visit Current infective exacerbation or reduction in lung function requiring therapeutic intervention
- •3\. Current moderate haemoptysis (greater than streaking in the sputum)
- •4\. Current dependency on positive pressure support with ACT Previous history of spontaneous rib fractures
- •5\. Pregnancy Inability to give consent for treatment or measurement
- •6\. Current dependency upon non\-invasive ventilation Current dependency upon oxygen therapy
Outcomes
Primary Outcomes
Not specified
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