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临床试验/NCT00785564
NCT00785564已完成不适用

Imaging Cardiac Electrical Remodeling With ECGI

Washington University School of Medicine1 个研究点 分布在 1 个国家目标入组 13 人开始时间: 2007年11月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
13
试验地点
1
主要终点
ECGI Image

研究概览

简要总结

A consequence of chronic RV pacing is a process of electrical remodeling that alters myocardial repolarization to reflect the altered depolarization induced by the RV lead. When RV pacing is discontinued, the altered repolarization persists for several weeks. This phenomena is traditionally described as "T-wave memory" based upon the 12-lead ECG appearance of inverted T-Waves. The investigators are using the ECGI technique to produce three dimensional electroanatomical images of this phenomena in patients with dual chamber pacemakers. Echocardiography will also be used to image the mechanical effects of RV pacing and T-wave memory. The images will show the spatial distribution of altered repolarization and allow us to correlate any mechanical consequences of this phenomena that may exist.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Implanted dual chamber pacemaker for sick sinus syndrome with no history of complete heart block.

排除标准

  • Persistent atrial fibrillation that is not suppressed by medications.

结局指标

主要结局

ECGI Image

时间窗: 1 month after RV pacing

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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