Comparative study on efficacy of intralesional botulinum toxin injection, intralesional steroid, and topical vitaminD/steroids combination injection in nail psoriasis patients
- Conditions
- ail psoriasis patients with at least 4 fingernails involvement.nail psoriasis, psoriatic nail, botulinum toxin injection
- Registration Number
- TCTR20210704002
- Lead Sponsor
- Chulabhorn International College of Medicine, Thammasat University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 18
1. Patient aged at least 20 years old.
2. Psoriatic nail patients who have at least 4 psoriatic nails.
3. Each enrolled nail has target NAPSI score at least 3 points.
1. Patients refusel to participate the study
2. Patients are using topical nail therapies within 2 weeks.
3. Patients are receiving oral therapies within 4 weeks.
4. Patients have active nail infection.
5. Patient with sensitivity or allergy to constituents of the botulinum toxin product, vitamin D , corticosteroid, cows milk protein or lidocaine
6. Patient with neuromuscular disorder or peripheral motor neuropathic disease (e.g. amyotrophic lateral sclerosis, myasthenia gravis, Lambert Eaton syndrome, myopathies)
7. Pregnancy or breastfeeding
8. Unrealistic expectation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method nail psoriasis at 4 and 6 months after end of the first intervention target NAPSI score,Pain of nail injection at 0 and 8 weeks of intervention pain score 0-10,Complication of nail psoriasis treatment at 8, 16, and 24 weeks side effect
- Secondary Outcome Measures
Name Time Method Satisfaction of nail psoriasis improvement at 8, 16, and 24 weeks Patient's satisfaction 0-4