Evaluation of Autogenous Tooth- Derived Graft With Bovine Bone For Surgical Repair of Unilateral Alveolar Cleft
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- visual analogue scale
研究概览
简要总结
The aim of this study is evaluation of autogenous tooth-derived graft combined with bovine bone for surgical repair of unilateral alveolar cleft .
详细描述
Decalcified dentin graft is thought to be a good graft material that can substitute existing autogenous bone graft materials. It can be easily and readily available, with minimal risk of infection, minimal donor site morbidity as no vital bone is sacrificed, it can be easily shaped to fit into the bony defect and it can be used as block or in powder forms, the hypothesis is to evaluate the biological and the physical properties of both and autogenous tooth derived graft and bovine bone to increase the quality and density of newly formed bone in alveolar cleft grafting
Criteria of patient selection:
Inclusion Criteria:
Patients with unilateral alveolar clefts requiring repair. patients free from any systemic disease that may affect normal healing of bone. patients in an age 7y up to 14 y. patients have teeth to be sacrificed, as primary teeth, carious teeth, malposed teeth, supernumerary tooth& non functional tooth in the study group.
Exclusion criteria:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 7 Years 至 14 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with unilateral alveolar clefts requiring repair.
- •patients free from any systemic disease that may affect normal healing of bone.
- •patients in an age 7y up to 14 y.
- •patients have teeth to be sacrificed, as primary teeth, carious teeth, malposed teeth, supernumerary tooth& non functional tooth in the study group.
排除标准
- •Bilateral alveolar clefts.
- •Immunocompromized patients.
- •Syndromic patients.
- •Patients have good full set of teeth, cannot be sacrified in study group
研究组 & 干预措施
autogenous tooth graft combined with bovine bone
This include 8 patients with unilateral alveolar cleft which will be repaired using autogenous tooth graft combined with bovine bone .
干预措施: autogenous tooth graft combined with bovine bone (Procedure)
bovine bone
This include 8 patients in whom alveolar cleft will be repaired using bovine bone .
干预措施: bovine bone (Procedure)
结局指标
主要结局
visual analogue scale
时间窗: 1 month
0 representing no pain and 10 representing the highest level of pain
inflammation score scale
时间窗: 1 month
0 no inflammation, 1-3 mild inflammation,4-7 moderate inflammation,8-10 severe inflammation
次要结局
- bone mineral density(6 months)
研究者
Marwa Taha Ibrahim
Ass Prof
Tanta University