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Clinical Trials/ISRCTN15521056
ISRCTN15521056
Completed
Phase 2

Chemoradiation for irresectable (T4) oesophageal cancer: a phase II multicentre study

Erasmus Medical Centre (The Netherlands)0 sites54 target enrollmentFebruary 27, 2007
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Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Not specified
Sponsor
Erasmus Medical Centre (The Netherlands)
Enrollment
54
Status
Completed
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

2006 Results article in https://doi.org/10.1038/sj.bjc.6603134 (added 26/08/2021)

Registry
who.int
Start Date
February 27, 2007
End Date
January 1, 2007
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
Erasmus Medical Centre (The Netherlands)

Eligibility Criteria

Inclusion Criteria

  • •1\. T4 N0\-1 M0
  • •2\. Tumour length less than 10 cm
  • •3\. Upper tumour border 2 cm of upper oesophageal sphincter
  • •4\. Tumour must not extend more than 4 cm into the stomach
  • •5\. World Health Organisation (WHO) grade zero to two
  • •6\. Adequate haematological, renal, hepatic and pulmonal function
  • •7\. Adequate caloric\- and/or fluid intake

Exclusion Criteria

  • •1\. Previous chemotherapy and or radiotherapy on mediastinum or upper abdomen
  • •2\. Myocardial Infarction (MI) within last six months
  • •3\. Ventricular arrhythmia or congestive heart failure
  • •4\. Second or third degree heart blocks
  • •5\. Pre\-existing neurotoxicity more than grade one
  • •6\. Active infection

Outcomes

Primary Outcomes

Not specified

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