Chemoradiation for irresectable (T4) esophageal cancer, a phase II multicenter study.
Completed
- Conditions
- Esophageal cancer
- Registration Number
- NL-OMON20123
- Lead Sponsor
- ot applicable
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 43
Inclusion Criteria
1. T4N0-1M0;
2. tumour length <10 cm;
Exclusion Criteria
1. Previous chemotherapy and or radiotherapy on mediastinum or upper abdomen;
2. MI within last 6 months;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine clinically complete biopsy proved response rate after a chemotherapy regime for patients with locally irresectable carcinoma of the esophagus or gatric junction without distant metastases (stage T4N0-1MO).<br /><br>To evaluate toxicity of this chemotherapy regimen in this group of patients.
- Secondary Outcome Measures
Name Time Method To determine time to progression (TTP) of the disease after treatment. To determine quality of life before, during and after treatment. To obtain insight in survival after treatment.