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Clinical Trials/ChiCTR-IOC-16007882
ChiCTR-IOC-16007882Active, not recruitingNot Applicable

慢性子宮內膜炎在生殖障礙中作用的研究

Department of Obstetrics and Gunaecology, The Chinese University of Hong Kong1 site in 1 country300 target enrollmentStarted: January 1, 1990Last updated:
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Trial Snapshot

Phase
Not Applicable
Status
Active, not recruiting
Sponsor
Enrollment
300
Locations
1
Primary Endpoint
endometrial response to infection as measured by plasma cell count, uNK cell count and Toll like receptor expression in archived endometrial tissue specimen from several groups of women with reproductive failure.
Study OverviewStudy DesignEligibility CriteriaArms & InterventionsOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

慢性子宮內膜炎在生殖障礙中作用

Study Design

Study Type
病因学/相关因素研究
Primary Purpose
单臂

Eligibility Criteria

Ages
20 to 40 (—)
Sex
Female

Inclusion Criteria

  • •Aged 20-40 years;
  • •Women with recurrent miscarriage, recurrent implantation failure, or with infertility undergoing IVF treatment.

Exclusion Criteria

  • •Uncorrected uterine anomalies, such as septate or bicornuate uterus, fibroids (submucous/intramural);
  • •Intrauterine adhesions;
  • •Adenomyosis;
  • •Systematic disease that may cause subfertility, such as diabetes or systemic lupus erythematosus.

Arms & Interventions

Case series

This project is an observational one. During the study, the procedure would be the same as per current practice,except saving two inner catheters instead of one.

Outcomes

Primary Outcomes

endometrial response to infection as measured by plasma cell count, uNK cell count and Toll like receptor expression in archived endometrial tissue specimen from several groups of women with reproductive failure.

Secondary Outcomes

  • Microbiome in uterine fluid at time of ET will be examined, as well as correlate findings with the various clinical outcomes of ET.

Investigators

Sponsor
Department of Obstetrics and Gunaecology, The Chinese University of Hong Kong

Study Sites (1)

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