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Measurement of mRNA of predictive factors to chemotherapy in patients with superficial bladder cancer

Not Applicable
Conditions
bladder cancer
Registration Number
JPRN-UMIN000003558
Lead Sponsor
Department of Urology, Keio University School of Medicine
Brief Summary

In patients with 28 T1G3 bladder cancer, Elevated DPD mRNA level was significantly associated with recurrence (p=0.048) and progression (p=0.045). However, TS and OPRT mRNA levels were not significantly associated with any other clinical features or outcomes.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
50
Inclusion Criteria

Not provided

Exclusion Criteria

The patients who have active other cancers, or received the treatment of bladder cancer at other hospital, or cannot come to hospital after operation regularly.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To evaluate the association between the values of TS, DPD and OPRT and 1)pathological staging (TNM classification), 2)grade, 3)recurrence, 4)progression 5) metastasis 6) death
Secondary Outcome Measures
NameTimeMethod
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