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临床试验/NCT00224588
NCT00224588已完成3 期

Effects of Peri Operative Administration of Ketamine on Long Term Post Thoracotomy Pain

Assistance Publique - Hôpitaux de Paris2 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2003年1月最近更新:
适应症
相关药物

试验速览

阶段
3 期
状态
已完成
入组人数
80
试验地点
2
主要终点
Long term (2 months) post thoracotomy pain was assessed using a french equivalent of the Mc Gill Pain score and pain area measurements in both groups

研究概览

简要总结

We assessed the effects of the N Methyl aspartate receptor antagonist Ketamine on long-term post thoracotomy pain. We hypothesized that ketamine could prevent supersensitization of the central nervous system involved in this chronic neuropathic pain.

详细描述

In this clinical, randomized prospective study, peri operative administration of ketamine was compared to placebo on long term post thoracotomy pain after a 2 months follow up period.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double

入排标准

年龄范围
80 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients eligible for thoracotomy or pneumectomy

排除标准

  • 未提供

结局指标

主要结局

Long term (2 months) post thoracotomy pain was assessed using a french equivalent of the Mc Gill Pain score and pain area measurements in both groups

次要结局

  • Analogic pain scores at rest and after coughing

研究者

申办方类型
Other

研究点 (2)

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