Biomarkers of Pain and Stress Perception and Dry Needling Technique Application

Not Applicable

Completed

• Conditions: Low Back Pain
• Interventions: Other: Dry needling of lumbar iliocostalis muscle; Other: Sham dry needling lumbar iliocostalis muscle

• Registration Number: NCT06355752
• Lead Sponsor: University of Alcala

Brief Summary

The use of the dry needling technique has become widespread in recent years for the treatment of musculoskeletal pain. Although dry needling has been shown to be effective in the treatment of shoulder pain, elbow pain, headache, etc., we do not yet have a clear understanding of the mechanisms of action that justify its beneficial effects.

In this study, we propose to analyse the biochemical markers of pain generated by the application of a dry needling technique on the lumbar musculature in patients with mechanical lumbar pain of non-specific origin.

The aim of this study will be to evaluate the effects of dry needling technique on the plasmatic concentration of biochemical markers.Furthermore, the test subjects will be randomly distributed into two groups.

An experimental group where the subjects will receive a real dry needling technique.

Another group will be treated with a sham technique.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-04-04
• Study First Submitted QC: 2024-04-04
• Study First Posted: 2024-04-09
• Study Start: 2024-04-12
• Status Verified: 2024-12
• Primary Completion: 2024-12-15
• Study Completion: 2024-12-15
• Last Update Submitted: 2024-12-18
• Last Update Posted: 2024-12-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• Mechanical lumbar pain of more than three months of evolution.

Exclusion Criteria

• Medical diagnosis of lumbar disc herniation or protrusion.
• Low back and leg pain.
• Pregnancy.
• Fibromyalgia.
• Fear of needles.
• Medication with anticoagulants

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Real dry needling	Dry needling of lumbar iliocostalis muscle	Subjects included in this group will receive a session with dry needling in the quadratus lumborum muscle.
Sham dry needling	Sham dry needling lumbar iliocostalis muscle	Subjects included in this group will receive a session with sham dry needling in the quadratus lumborum muscle.

Primary Outcome Measures

Name	Time	Method
Extracting Blood Samples and Obtaining Serum/Plasma	Change from Baseline concentration at 2 hours	Serum samples will be extracted by venipuncture at the cubital fossa, according to a standardized protocol. Blood will be collected in a tube for serum (Vacutainer SST II Advance, model 367953) and a tube for plasma (Vacutainer PST II Advance, model 367374) separation. Substances related to antinociception will be determined later: Dopamine, adrenaline, norepinephrine, cortisol.

Trial Locations

Locations (1)

Centro Investigación Fisioterapia y Dolor; 🇪🇸 Alcalá De Henares, Madrid, Spain