Randomized, Active-controlled, Clinical Trial Comparing Effects of Mindfulness and Interpersonal Effectiveness Skills in Borderline Personality Disorder
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 64
- 主要终点
- change from baseline in borderline symptoms after a 10 week intervention
研究概览
简要总结
The purpose of the study was to determine whether mindfulness training could be more effective than another active intervention in reducing borderline personality disorder (BPD) symptoms. The main hypothesis was that patients allocated to the mindfulness group would show a greater improvement on global BPD symptomatology. As a second objective, we explored some of the possible underlying mechanisms of both active treatments. For that purpose, changes in decentering, mindfulness facets and cognitive processing of social interactions were also evaluated.
详细描述
The present study aimed at evaluating the efficacy of mindfulness skills (M) versus interpersonal effectiveness skills (IE) on borderline symptoms. For that purpose, a randomized, active-controlled clinical trial was designed. 64 participants with borderline personality disorder (BPD) diagnosis were allocated to mindfulness (n=32) or interpersonal effectiveness skills (n=32). Both interventions were delivered over a 10-week period. The borderline symptom list (BSL-23) was elected as the primary outcome measure. Mindfulness related capacities, decentering and cognitive processing of social interactions were also evaluated with the Five Facet Mindfulness Questionnaire (FFMQ), the Experiences Questionnaire (EQ) and the Multidimensional Scale of Social Expression (EMES-C), respectively. Assessments were conducted pre and post interventions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ages between 18 and 45 years
- •BPD criteria according to two diagnostic interviews (SCID-II and DIB-R)
排除标准
- •Lifetime diagnosis of schizophrenia, drug-induced psychosis, organic brain syndrome, bipolar disorder or mental retardation
- •Participating in any sort of psychotherapy during the study or having participated in dialectical behavioral therapy groups in the past
结局指标
主要结局
change from baseline in borderline symptoms after a 10 week intervention
时间窗: 10 weeks
participants were assessed pre and post interventions
次要结局
- change from baseline in social interactions after a 10 week intervention(10 weeks)
- change from baseline in decentering after a 10 week intervention(10 weeks)
- change from baseline in mindfulness facets after a 10 week intervention(10 weeks)
研究者
Juan Carlos Pascual
Psychiatrist
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau