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Clinical Trials/NCT02397031
NCT02397031
Completed
N/A

Randomized, Active-controlled, Clinical Trial Comparing Effects of Mindfulness and Interpersonal Effectiveness Skills in Borderline Personality Disorder

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau0 sites64 target enrollmentSeptember 2011

Overview

Phase
N/A
Intervention
Not specified
Conditions
Borderline Personality Disorder
Sponsor
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Enrollment
64
Primary Endpoint
change from baseline in borderline symptoms after a 10 week intervention
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

The purpose of the study was to determine whether mindfulness training could be more effective than another active intervention in reducing borderline personality disorder (BPD) symptoms. The main hypothesis was that patients allocated to the mindfulness group would show a greater improvement on global BPD symptomatology. As a second objective, we explored some of the possible underlying mechanisms of both active treatments. For that purpose, changes in decentering, mindfulness facets and cognitive processing of social interactions were also evaluated.

Detailed Description

The present study aimed at evaluating the efficacy of mindfulness skills (M) versus interpersonal effectiveness skills (IE) on borderline symptoms. For that purpose, a randomized, active-controlled clinical trial was designed. 64 participants with borderline personality disorder (BPD) diagnosis were allocated to mindfulness (n=32) or interpersonal effectiveness skills (n=32). Both interventions were delivered over a 10-week period. The borderline symptom list (BSL-23) was elected as the primary outcome measure. Mindfulness related capacities, decentering and cognitive processing of social interactions were also evaluated with the Five Facet Mindfulness Questionnaire (FFMQ), the Experiences Questionnaire (EQ) and the Multidimensional Scale of Social Expression (EMES-C), respectively. Assessments were conducted pre and post interventions.

Registry
clinicaltrials.gov
Start Date
September 2011
End Date
April 2014
Last Updated
11 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Responsible Party
Principal Investigator
Principal Investigator

Juan Carlos Pascual

Psychiatrist

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Lifetime diagnosis of schizophrenia, drug-induced psychosis, organic brain syndrome, bipolar disorder or mental retardation
  • Participating in any sort of psychotherapy during the study or having participated in dialectical behavioral therapy groups in the past

Outcomes

Primary Outcomes

change from baseline in borderline symptoms after a 10 week intervention

Time Frame: 10 weeks

participants were assessed pre and post interventions

Secondary Outcomes

  • change from baseline in social interactions after a 10 week intervention(10 weeks)
  • change from baseline in decentering after a 10 week intervention(10 weeks)
  • change from baseline in mindfulness facets after a 10 week intervention(10 weeks)

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