MedPath

The effect of topical nitroglycerin 0.2% on anal pain reductio

Phase 3
Conditions
Anal spasm
Proctalgia fugax.
Registration Number
IRCT2015122212789N12
Lead Sponsor
Vice Chancellor for Research ,Kurdistan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
40
Inclusion Criteria

Inclusion criteria including:
1.Consent to participate in the study
2.Patients with recurrent episodes of severe pain localized in the lower rectum and anus area, and the episodes of pain lasting a few seconds up to 20 minutes and there was no pain between episodes.
Exclusion criteria including:
1.Any proved pathology during clinical history, physical examination and rectosigmoidoscopy in anorectal including (Hemorrhoids, ischemia, anal abscess, anal fissure, rectocele, malignancy, inflammation, anal prolapsed).
2.History of trauma, urinary tract infection, surgery and hysterectomy in recent 6 months
3.Associated symptoms (fever, change in stool consistency, anemia, anal secretions, abdominal pain, weight loss and rectal bleeding).
4.History of heart and neurological disease and aortic stenosis
5.History of hypotension
6.Chronic proctalgia
7.Unwillingness to continue participating in the study
8.Single rectal ulcer

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pain severity. Timepoint: The second week, three months and six months after treatment. Method of measurement: Visual Analog Scale.
Secondary Outcome Measures
NameTimeMethod
The repetition of pain. Timepoint: The second week, three months and six months after treatment. Method of measurement: questionnaire.
© Copyright 2025. All Rights Reserved by MedPath