Reducing Hippocampal Hyperactivity and Improving Cognition in Schizophrenia
Phase 1
Completed
- Conditions
- Schizophrenia
- Registration Number
- NCT03034356
- Lead Sponsor
- VA Office of Research and Development
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 67
Inclusion Criteria
Inclusion Criteria:<br><br> - Diagnosis of schizophrenia or schizoaffective disorder<br><br> - Good general health<br><br> - Normal vital signs (blood pressure, pulse, respiration)<br><br>Exclusion Criteria:<br><br> - Substance abuse<br><br> - Significant neurological disorders<br><br> - Significant head trauma/injury<br><br> - Pregnancy<br><br> - MRI-specific exclusion criteria, e.g.,:<br><br> - claustrophobia<br><br> - weight>400 lbs<br><br> - metal in the body
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Neurocognitive function
- Secondary Outcome Measures
Name Time Method Resting-state neuronal response