Lung USG VS chest auscultation as a marker of atropinisation in patients with acute organophosphate poisoning
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To compare the time and amount of atropine required for atropinisation in case of acute organophosphate poisoning on using lung USG vs chest auscultation as a marker of atropinisation.
研究概览
简要总结
This is a randomised controlled trial comparing lung us vs chest auscultation as marker of atropinisation in patients with acute organophosphorus poisoning . Lung USG has a diagnostic accuracy of 95% for detecting alveolar interstitial syndromes compared to 55% with chest auscultation. We intend to include patients with OP poisoning with age above 18 years. Here we will compare the amount of atropine required for atropinisation in OP poisoning patients using lung USG vs chest auscultation as marker of atropinisation. Our sample size is 40.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients above 18 years of age from either gender with history of acute organophosphate poisoning presenting within 24hours and its clinical toxidrome.
- •Patients who are willing to give informed consent and actively participate in the study.
排除标准
- •Patients with any other poisoning other than organophosphorus compounds.
- •Patients with history of heart diseases or other causes of pulmonary oedema / lower respiratory tract infection or other pulmonary co-morbidities.
- •Patients requiring mechanical ventilation.
结局指标
主要结局
To compare the time and amount of atropine required for atropinisation in case of acute organophosphate poisoning on using lung USG vs chest auscultation as a marker of atropinisation.
时间窗: To compare the time and amount of atropine required for atropinisation in case of acute organophosphate poisoning on using lung USG vs chest auscultation as a marker of atropinisation.
次要结局
- 1. To compare the patient outcome in terms of mortality/ ICU admission/ discharge.(2. To compare the development of intermediate syndrome in patients)
研究者
Dr Satyabrata Guru
AIIMS,Bhubaneswar