Effect of periodically versus continuously OCP on Endometrioma recurrence
Phase 3
- Conditions
- ?????????? ??????.Endometriosis of ovary
- Registration Number
- IRCT20140111016161N8
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 134
Inclusion Criteria
Development of endometrioma
Age range from 18 to 35 years
Unwillingness to pregnancy
Anti-Müllerian hormone (AMH) higher than 2.5
Laparoscopic excision of endometrioma
Exclusion Criteria
Receive other therapies during the last 6 months (except for non-steroidal anti-inflammatory drugs)
Contraindication for estrogen and progesterone regular use
Unwillingness to change in menstrual cycles
Pelvic inflammatory diseases
Varicose veins
known malformations of the genitourinary system in previous surgeries
known urological, orthopedics, gastrointestinal disorders, and psychological disorder.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain. Timepoint: 3, 6 and 12 months after treatment starting. Method of measurement: Visual Analogue Scale.;Anatomical recurrence of ovary endometrium. Timepoint: 3, 6 and 12 months after treatment starting. Method of measurement: sonography.
- Secondary Outcome Measures
Name Time Method Drug Complications (Increased Endometrial Thickness). Timepoint: 3, 6, and 12 months after starting treatment. Method of measurement: Ultrasound.;Drug Complications (Venous thrombosis). Timepoint: 3, 6, and 12 months after starting treatment. Method of measurement: Medical history and physical examination.