Improving Immunization Rates in Transplant Candidates Through the Use of a Health Information Technology Tool

Not Applicable

• Conditions: Transplantation Infection; Vaccination
• Interventions: Other: immunization app

• Registration Number: NCT04336735
• Lead Sponsor: University of Colorado, Denver

Brief Summary

Vaccine preventable infections are a serious complication following pediatric solid organ transplant. Immunizations are a minimally invasive and cost-effective was to reduce these infections. Despite the importance of pre-transplant vaccination, the majority of pediatric solid organ transplant recipients are not up-to-date on age-appropriate immunizations at the time of transplant. The goal of this study is to pilot a novel health information technology immunization tool to improve immunization rates in pediatric solid organ transplant candidates.

Detailed Description

Triads of parents, primary care physicians, and transplant sub-specialists will be enrolled to use a pre-transplant immunization tool while their child awaits transplant. The tool will provide information about vaccines, information about vaccine-preventable infections in the transplant population, a central easily accessible vaccine record, and a communication portal. The tool will also send vaccine reminders when vaccinations are due. The investigators will assess 1) the effectiveness of the tool in improving pre-transplant immunization rates, 2) the acceptability of the tool to users and 3) the feasibility of the tool.

Study Timeline

• Study First Submitted: 2020-04-03
• Study First Submitted QC: 2020-04-03
• Study First Posted: 2020-04-07
• Status Verified: 2022-01
• Study Start: 2022-01-01
• Last Update Submitted: 2022-01-10
• Last Update Posted: 2022-01-12
• Primary Completion: 2024-08
• Study Completion: 2024-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• Parent, primary care provider and sub-specialist of a child awaiting heart, liver or kidney transplant

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Exclusion Criteria

• Non English speaking
• No access to a smart phone or computer

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Immunization Tool Users	immunization app	Users will trial a novel transplant-specific immunization tool (app)

Primary Outcome Measures

Name	Time	Method
Effectiveness of Transplant Immunization Tool, as measured by number of patients with up-to-date vaccinations	Date of transplantation (up to 3 years post-enrollment)	We will assess whether the novel immunization tool improves pre-transplant vaccination rates. The number of participants who are up to date with vaccinations will be reported.

Secondary Outcome Measures

Name	Time	Method
Acceptability and Feasibility of the Transplant Immunization Tool, as assessed by a questionnaire	Date of transplantation (up to 3 years post-enrollment)	We will assess whether the novel immunization tool is feasible and acceptable to users using a Likert scale with possible scores of 1-5, with 1 being least feasible/acceptable to the participant and 5 being the most feasible/acceptable.

Trial Locations

Locations (1)

Childrens Hospital Colorado; 🇺🇸 Aurora, Colorado, United States