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Study Comparing Weekly Taxol and Carboplatin vs Standard Taxol and Carboplatin Regimen for Stage IIIB or IV Non-Small-Cell Lung Cancer

Phase 3
Completed
Conditions
Carcinoma, Non-Small-Cell Lung
Registration Number
NCT00035152
Lead Sponsor
Bristol-Myers Squibb
Brief Summary

Taxol and carboplatin are commonly used drugs for the treatment of stage IIIB or IV non small cell lung carcinoma.

This study compares treatment with Taxol/carboplatin given every 3 weeks to a schedule where it is given weekly.

The purpose of the study is to determine the most effective and safe schedule for giving these drugs in non small cell lung carcinoma.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
444
Inclusion Criteria

Not provided

Exclusion Criteria
  • Past or current history of neoplasm other than the entry diagnosis. Exceptions are curatively treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix or other cancers treated by surgery or radiation with a disease free survival longer than 5 years.
  • Patients who have undergone surgery less than 3 weeks prior to enrollment.
  • History of serious cardiac disease not adequately controlled.
  • Patients with serious active infections or other serious underlying medical condition.
  • Uncontrolled diabetes mellitis.

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (56)

Hennepin County Medical Center

🇺🇸

Minneapolis, Minnesota, United States

Siouxland Hematology/Oncology Associates

🇺🇸

Sioux City, Iowa, United States

Wellstar Cobb Hospital

🇺🇸

Austell, Georgia, United States

West Suburban Center for Cancer Care

🇺🇸

River Forest, Illinois, United States

Naval Medical Center

🇺🇸

San Diego, California, United States

Little Rock Hematology/Oncology Associates

🇺🇸

Little Rock, Arkansas, United States

Community Cancer Care, Inc.

🇺🇸

Indianapolis, Indiana, United States

Mid Illinois Hematology and Oncology Associates, Ltd.

🇺🇸

Normal, Illinois, United States

Good Samaritan Medical Center

🇺🇸

West Palm Beach, Florida, United States

Mercy Cancer Center

🇺🇸

Mason City, Iowa, United States

Medical Oncology Care Associates

🇺🇸

Orange, California, United States

Beth Israel Deaconess Medical Center

🇺🇸

Boston, Massachusetts, United States

Joliet Oncology/Hematology Associates,Ltd.

🇺🇸

Joliet, Illinois, United States

Ellis Fischel Cancer Center

🇺🇸

Columbia, Missouri, United States

Maine General Medical Center

🇺🇸

Waterville, Maine, United States

Hematology and Oncology Associates of Southern Michigan,P.C

🇺🇸

Jackson, Michigan, United States

Fairview-University Medical Center, University of Minnesota

🇺🇸

Minneapolis, Minnesota, United States

Metro Minnesota CCOP

🇺🇸

St. Louis Park, Minnesota, United States

New Mexico Oncology Hematology Consultants

🇺🇸

Albuquerque, New Mexico, United States

Advanced Oncology Associates

🇺🇸

Armonk, New York, United States

Hematology-Oncology of Central New Jersey

🇺🇸

Red Bank, New Jersey, United States

The Center for Cancer and Hematologic Disease

🇺🇸

Cherry Hill, New Jersey, United States

Brooklyn VA

🇺🇸

Brooklyn, New York, United States

Goshen Medical Associates

🇺🇸

Goshen, New York, United States

New York Oncology-Hematology,P.C./Capital District Hematology, Oncology Associates

🇺🇸

Latham, New York, United States

Quadrangle Medical Specialists, Southern Oncology Research

🇺🇸

Greenville, North Carolina, United States

Columbus CCOP

🇺🇸

Columbus, Ohio, United States

Upstate New York Cancer R & E

🇺🇸

Rochester, New York, United States

Clifton Springs Hospital and Clinic

🇺🇸

Clifton Springs, New York, United States

Raleigh Hematology Associates, Wake Practice

🇺🇸

Cary, North Carolina, United States

Guthrie Clinic Ltd

🇺🇸

Sayre, Pennsylvania, United States

Hematology/Oncology of Rockland

🇺🇸

New York, New York, United States

Albert Einstein Healthcare Network

🇺🇸

Philadelphia, Pennsylvania, United States

Don & Sybil Harrington Cancer Center

🇺🇸

Amarillo, Texas, United States

Mid Dakota Clinic

🇺🇸

Bismarck, North Dakota, United States

Southwest Cancer Center

🇺🇸

Lubbock, Texas, United States

Central Pennsylvania Hematology & Medical Oncology Associates, P.C.

🇺🇸

Lemoyne, Pennsylvania, United States

Northwest Medical Specialties, PLLC

🇺🇸

Tacoma, Washington, United States

Maimonides Medical Center

🇺🇸

Brooklyn, New York, United States

Associated Physicians & Surgeons Clinic, LLC

🇺🇸

Terre Haute, Indiana, United States

Walter Reed Army Hospital

🇺🇸

Washington, District of Columbia, United States

Madigan Army Medical Center

🇺🇸

Tacoma, Washington, United States

University of Pittsburgh Medical Center/University of Pittsburgh Cancer Institute

🇺🇸

Pittsburgh, Pennsylvania, United States

Genesis Cancer Center

🇺🇸

Hot Springs, Arkansas, United States

University of Louisville

🇺🇸

Louisville, Kentucky, United States

Creighton University Cancer Center

🇺🇸

Omaha, Nebraska, United States

Highlands Oncology Group

🇺🇸

Springdale, Arkansas, United States

Danbury Hospital/Praxair Cancer Center

🇺🇸

Danbury, Connecticut, United States

Louisiana State University Health Sciences Center

🇺🇸

Shreveport, Louisiana, United States

Boston Cancer Group, PLC

🇺🇸

Memphis, Tennessee, United States

Louisiana Oncology Associates

🇺🇸

Lafayette, Louisiana, United States

Community Medical Center

🇺🇸

Toms River, New Jersey, United States

Brackenridge Hospital

🇺🇸

Austin, Texas, United States

Southwest Regional Cancer Center

🇺🇸

Austin, Texas, United States

Jewish Medical Plaza

🇺🇸

Louisville, Kentucky, United States

Washington VA Medical Center

🇺🇸

Washington, District of Columbia, United States

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