Immediate Exercise-Induced Hypoalgesia in Patients With Chronic Low Back Pain
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 83
- 试验地点
- 1
- 主要终点
- Pressure pain threshold
研究概览
简要总结
The main objective of this study is:
• To evaluate the immediate hypoalgesic effect of an aerobic exercise session of different intensities in patients with chronic low back pain;
The secondary objective is:
• To explore whether pain intensity, level of physical activity, functionality, catastrophizing, kinesiophobia, anxiety and depression interfere with the immediate hypoalgesic effect of exercise.
详细描述
There will be 3 groups of participants, an asymptomatic control group that will not perform any exercise and two groups of individuals with low back pain. One group will perform exercise at 90% VO2máx and the other at 60% VO2máx.
All the three groups will be assessed at baseline for pressure pain threshold, pain intensity, pain phenotype, disability, kinesiophobia, catastrophizing, anxiety and depression, physical activity, and aerobic capacity. In addition, pressure pain threshold and pain intensity will also be assessed at post-intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All groups:
- •age between 18 and 65 years old
- •Participants with low back pain:
- •non-specific LBP (defined as pain between the costal margins and the inferior gluteal folds, which is usually accompanied by painful limitation of movement and may be associated with pain referred down to the leg)
排除标准
- •All groups:
- •presence of pathology of the nervous system, cardiovascular or carcinogenic, rheumatic diseases (for example, rheumatoid arthritis), fibromyalgia, previous history of lumbar surgery, medication that affects or alters heart rate, any contraindication to exercise and pregnancy.
结局指标
主要结局
Pressure pain threshold
时间窗: Post-intervention (approximately 45 minutes after baseline)
Pressure pain threshold measured with an algometer in Kgf
次要结局
- Physical activity(Baseline)
- Pain intensity(Post-intervention (approximately 45 minutes after baseline))
- Fear of movement(Baseline)
- Disability(Base)
- Anxiety and depression(Baseline)
- Catastrophizing(Baseline)
- Pain phenotype(Baseline)
- Aerobic capacity(Baseline)
- Symptoms of central sensitization(Baseline)
研究者
Anabela G Silva
Assistant Professor
Aveiro University