To assess the effect of the drug tranexamic acid on the blood loss and rate of blood transfusion by infiltrating it into the joint and by giving it directly into the vein in patients undergoing total knee replacement surgery.
Phase 4
- Conditions
- Health Condition 1: M171- Unilateral primary osteoarthritisof knee
- Registration Number
- CTRI/2019/01/017105
- Lead Sponsor
- Ganga Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Primary unilateral osteoarthritis of knee joint
Exclusion Criteria
Diagnosis other than primary osteoarthritis
Previous knee surgery
Inflammatory and infectious arthritis
Underlying coagulopathy
Post traumatic arthritis
Patients receiving anticoagulation therapy
History of thromboembolic & cardiovascular disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The final outcome will be measured in terms of total blood loss and need for any blood transfusionTimepoint: 2 Time Points .Immediate post operative and 4 weeks post opaerative
- Secondary Outcome Measures
Name Time Method Symptomatic Deep Venous Thrombosis,Wound Complications And InfectionTimepoint: 2 Time points.Immediate post operative and 4 weeks post operative