Clinical relevance of immature platelet fraction in thrombocytopenia and its role in differentiating bone marrow suppression and destruction of platelets
Not Applicable
- Conditions
- Health Condition 1: D61- Other aplastic anemias and other bone marrow failure syndromesHealth Condition 2: D69- Purpura and other hemorrhagic conditions
- Registration Number
- CTRI/2024/02/063089
- Lead Sponsor
- Kasturba Medical College MAHE Manipal RESEARCH GRANT
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All adults (18years and above) having thrombocytopenia with a definitive diagnosis
Exclusion Criteria
1) All pediatric patients
2) Samples with platelet clumps
3) Patients on drug therapy / chemotherapy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method • To determine immature platelet fraction in patients with thrombocytopenia using automated hematology analyzer (SYSMEX XN-1500) <br/ ><br> <br/ ><br>• To determine normal reference range of immature platelet fraction in healthy controlsTimepoint: 11 months (1 march 2023 to 28 february 2024)
- Secondary Outcome Measures
Name Time Method To determine whether immature platelet fraction can be used reliably to distinguish between hypo-productive thrombocytopenia and hyper-destructive thrombocytopeniaTimepoint: 11 months (1 march 2023 to 28 february 2024)