A New Prognostic Scoring System for Spontaneous Ruptured Hepatocellular
Completed
- Conditions
- Rupture, Spontaneous
- Interventions
- Procedure: Liver resection
- Registration Number
- NCT03504358
- Lead Sponsor
- Huazhong University of Science and Technology
- Brief Summary
Develop a new scoring system for HCC patients with tumor rupture.
- Detailed Description
There has been no special prognostic scoring system for HCC patients with tumor rupture in the literature. In this work, we obtained all survival risk factors of ruptured HCC patients who underwent partial hepatectomy using multivariable Cox regression analysis. Furthermore, we develop and validate a new postoperative scoring system for patients with spontaneous HCC rupture based on the these results.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 129
Inclusion Criteria
- Received partial hepatectomy; with Child A or B liver function.
Exclusion Criteria
- Without complete data；loss of follow-up; had reveived repeated transcatheter arterial chemoembolization before rupture; received non-radical resection.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Model comparison Liver resection Comparison of models in predicting survival Different risk group Liver resection Low-risk group, moderate-risk group, high-risk group Analysis before liver resection Liver resection Multivariate analysis of predictive factors associated with survival
- Primary Outcome Measures
Name Time Method Overall survival 3 years Overall survival after partial hepatectomy
- Secondary Outcome Measures
Name Time Method Disease-free survival 3 years Recurrence-free survival after partial hepatectomy