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Clinical Trials/NCT03695913
NCT03695913
Completed
Not Applicable

Continuous Glucose Monitoring With a Low Carbohydrate Diet to Reduce Weight in Patients With Pre-Diabetes

University of Michigan1 site in 1 country15 target enrollmentOctober 16, 2018
ConditionsPre-diabetes

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pre-diabetes
Sponsor
University of Michigan
Enrollment
15
Locations
1
Primary Endpoint
Participant Satisfaction With Continuous Glucose Monitoring
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

This study will recruit pre-diabetic patients to see if continuous glucose monitoring (CGM) with a low carbohydrate diet can reduce the percentage of time the CGM readings are above the normal range. Through this study it will demonstrate the feasibility of using CGM with a low carbohydrate diet to reduce weight and risk of developing diabetes in patients with pre-diabetes.

Patients that appear to be eligible will be recruited from Michigan Medicine in the Family Medicine Clinic at the Livonia Center.

Registry
clinicaltrials.gov
Start Date
October 16, 2018
End Date
September 26, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Caroline Richardson

Dr Max and Buena Lichter Research Professor of Family Medicine, Assistant Chair, Department of Family Medicine and Professor of Family Medicine, Medical School

University of Michigan

Eligibility Criteria

Inclusion Criteria

  • A1C Glucose Measurement between 5.7 to 6.4 (for most recent A1C test, not older than 1 year)
  • No diabetes medication including Metformin
  • BMI (body mass index) \>30
  • Must speak, read, and write in English
  • No current pregnancy or breastfeeding
  • Must not classify as either Vegan or Vegetarian
  • Must be a patient at the Livonia Health Center

Exclusion Criteria

  • previous bariatric surgery

Outcomes

Primary Outcomes

Participant Satisfaction With Continuous Glucose Monitoring

Time Frame: 60 days (30 days after visit 3 completion)

Common qualitative themes related to participant satisfaction with CGM from post intervention interview were coded.

Participant Satisfaction With Continuous Glucose Monitoring (CGM)

Time Frame: 33 days after day 1 (visit 3 completion)

Satisfaction is measured using responses to the post intervention survey question, "How likely are you to recommend that a friend or family member with pre-diabetes wear a continuous glucose monitor (CGM)?". A 5 point scale was used, ranging from 1 to 5, where a score of 1 is "extremely likely" and 5 is "would not recommend". Satisfied respondents answered either 1 or 2 on the scale.

Secondary Outcomes

  • Number of Participants Who Reported Side Effects of Low Carbohydrate Eating and CGM at Health Check Phone Call(Approximately 5 days each new sensor is placed (days 5 and 16))
  • Change in Knowledge of Low Carbohydrate Eating(baseline, day 22)
  • Feasibility, Measured by Recruitment(3 months)
  • Weight Change(day 11 (visit 2), day 22 (visit 3))
  • Change in Cravings From Day 11 to Day 22(11 days)
  • Intention to Continue Low Carbohydrate Eating(day 22)
  • Change in Percentage of Time Glucose is Above 140(33 days after day 1)
  • Feasibility of Pre-diabetic Patients to Wear CGM Sensors(completed within 60 days of enrollment)
  • Utility of CGM Feedback for Changing Diet(60 days (30 days after visit 3 completion))
  • Number of Participants Who Reported Side Effects of Low Carbohydrate Eating and CGM in Patient Log(days 11 through 22)

Study Sites (1)

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