Redistribution of renal flow and tubular inflammatio

Recruiting

• Conditions: occlusion of the renal artery; 10003216; Renal artery stenosis; 10029149

• Registration Number: NL-OMON30683
• Lead Sponsor: Academisch Ziekenhuis Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

- Scheduled PTRA, which procedure is clinically indicated by the presence of angiographically proven, symptomatic unilateral renal artery stenosis of >50% luminal diameter reduction.

Exclusion Criteria

- Recipients of a renal transplant, primary renal diseases or nephrectomy.
- Bilateral renal artery stenosis.
- Fibromuscular dysplasia.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Intrarenal hemodynamics (calculated from MRI signal-time curves and renal<br /><br>inulin/PAH clearance) and tubular damage (markers in the urine). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Renal and cardiovascular indices used in common clinical practice. </p><br>