Effects of altered microcirculation on renal function in transfemoral, transapical, and open aortic valve replacement.

• Conditions: I35.8; N17.2; Other aortic valve disorders; Acute renal failure with medullary necrosis

• Registration Number: DRKS00024765
• Lead Sponsor: Klinik für AnästhesiologieUniversitätsklinikum Heidelberg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-31
• Study Completion: 2022-09-10
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients with aortic valve replacement:
- Written informed consent by the study participant
- Age = 18 years
- Planned aortic valve replacement in the cardiology or cardiosurgery clinic of Heidelberg University Hospital

Healthy subjects:
- Written informed consent by the study participant
- Age = 18 years

Exclusion Criteria

Exclusion criteria common to all study groups:
- Failure to meet inclusion criteria.
- Infectious viral diseases (HBV, HCV, HIV, COVID-19) or unknown COVID-19 status.
- Refusal to participate in the study
- Pre-existing severe renal insufficiency with a glomerular (GFR) <15 ml/min/m2 or need for dialysis

Study & Design

• Study Type: observational
• Study Design: Not specified