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Efficacy Study Image Guided, Auto-Targeted Neurostimulation for the Treatment of Non-Specific Low Back Pain

Not Applicable
Completed
Conditions
Low Back Pain
Interventions
Device: Image Guided TENS (Auto-Targeted Neurostimulation, NeMa-st)
Registration Number
NCT01132300
Lead Sponsor
Bnai Zion Medical Center
Brief Summary

The purpose of this study is:

* Initial evaluation of the clinical effectiveness of Image Guided Transcutaneous Electrical Stimulation (TENS) device for treatment of non-specific low back pain.

* To assess the tolerability and acceptability of the device by the caregiver ("User Friendly").

* To evaluate patients' tolerance by monitoring side effects and tolerability during treatment.

Detailed Description

Transcutaneous electrical nerves stimulation (TENS) devices are a drug-free alternative for managing pain. For the past thirty years, doctors have been prescribing FDA approved TENS worldwide as an effective way to relieve pain. TENS device currently utilized includes a variety of types of devices and pulse modulations. Most of these devices are applied on large surface areas, and are designed to block the pain signal (gate mechanism) to the brain. Others manual TENS devices are applied to small surface areas to stimulate peripheral nerve ends, and by that causing the release of endorphins with a significantly superior clinical outcome. Such treatments are time consuming and cumbersome and requires previous knowledge of location of nerve ends.

A novel device capable of scanning a large skin surface area, automatically locating nerve ends responsible for pain relief by utilizing skin impedance measurements and image processing with anatomical matching will be tested for stimulating these peripheral nerve ends (NeMa-st, Nervomatrix Ltd., Netanya, Israel).

For this purpose an open study to initially evaluate safety and efficacy of the intervention is designed. 20 patients will undergo 2 treatment sessions per week for a period of 4 weeks, while maintaining their pain relief medication treatment regime.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
20
Inclusion Criteria
  • Non-specific low back pain persisted at least 1 month and no longer than 12 month before the study
  • Patients must have a baseline score>40 mm on the VAS pain scale
  • If taking analgesics, patients must agree to maintain a steady regimen for the duration of the study.
  • Able to provide written and verbal informed consent.
Exclusion Criteria
  • Sciatica
  • Diagnosed spinal stenosis
  • Back Pain potentially attributable to specific underlying diseases or conditions (e.g. pregnancy, metastatic cancer, spondylolisthesis, fractured bones, dislocated joints, disc eruption).
  • Unstable medical or severe psychiatric conditions or dementia.
  • Previous Back surgery
  • Physically unable to undergo treatment
  • Patients receiving workers compensation or those involved in litigation
  • Minimal pain - less than 40mm score on VAS scale
  • History of pacemaker , implantable devices, history of cardiac arrhythmias
  • Allergy or intolerance to adhesive materials
  • Clinical evidence of cardiovascular, pulmonary, renal, hepatic, neurological , hematological or endocrine abnormalities.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
TreatmentImage Guided TENS (Auto-Targeted Neurostimulation, NeMa-st)-
Primary Outcome Measures
NameTimeMethod
Visual Analogue Scale Pain Questionnaire (VAS)Baseline, before, and two hours after treatment session, 2 times a week, up to 5 weeks
Secondary Outcome Measures
NameTimeMethod
Oswestry Disability Questionnaireonce a week during the study, up to 5 weeks
Side effect recordafter each treatment session, 2 times a week, up to 5 weeks
Range of Motion - lower back and pelvic forward flexionBaseline, once a week, up to 5 weeks

Trial Locations

Locations (1)

Bnai Zion Medical Center

🇮🇱

Haifa, Israel

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