A clinical trial to study the effects of two drugs, Shigru kwatha and Livogrit in patients with Non Alcoholic Fatty Liver Disease

Phase 2

Conditions: Health Condition 1: K759- Inflammatory liver disease, unspecified

Registration Number: CTRI/2023/10/058382

Lead Sponsor: Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1. Patient between the age group of 18 to 65 years will be selected.

2. Patient irrespective of gender, religion, occupation and chronicity will be selected for the study.

3. Both fresh and treated cases would be taken for the study.

4. Patient with Grade 1 and Grade 2 fatty liver only will be selected for the study.

5. Individual with controlled Diabetes Mellitus having Grade 1 and Grade 2 fatty liver will be selected for the study.

Exclusion Criteria

1.Pregnant or lactating women will be excluded.

2. Patient who have had Hepatitis B,C or other hepatic viral infection , autoimmune hepatitis and drug induced hepatitis or alcoholic hepatitis will be excluded.

3. Patient with severe complication of the cardiovascular, renal or hematopoietic systems and mental disease will be excluded.

4. Patient will be excluded having decompensated liver disease.

5. Patient with prolonged or a history of ascites , developed Hepatocellular carcinoma Hepatic Encephalopathy , Variceal bleeding will be excluded.

6. Patient with a history of using IFN or antiviral agents or Corticosteroids or Immunosuppresive drugs will also be excluded.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Subjective criteria <br/ ><br>1. Anorexia <br/ ><br>2. Fatigue <br/ ><br>3. Abdominal pain <br/ ><br>4. Malaise <br/ ><br>5. Indigestion(avipaka) <br/ ><br>6. Polydipsia (pipasa) <br/ ><br>7. Constipation <br/ ><br>8. Vomiting (chhardi) <br/ ><br>9. Fever (mridu jwara) <br/ ><br>10. Flatulence (aanaha) <br/ ><br>11. TastelessnessTimepoint: 0th day 30th day 60th day

Secondary Outcome Measures